ÖZGEÇMİŞ. 1. Adı Soyadı: Emel Baloğlu 2. Doğum Tarihi: Ünvanı: Yrd. Doç. Dr. 4. Öğrenim Durumu:

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1 ÖZGEÇMİŞ 1. Adı Soyadı: Emel Baloğlu 2. Doğum Tarihi: Ünvanı: Yrd. Doç. Dr. 4. Öğrenim Durumu: Derece Alan Üniversite Yıl Lisans Tıp Fakültesi Ankara Üniversitesi 2000 Y.Lisans Tıp Fakültesi Ankara Üniversitesi 2000 Tıpta Uzmanlık Farmakoloji Ankara Üniversitesi Tıp Fakültesi, Farmakoloji ve Klinik Farmakoloji Anabilim Dalı Akademik Ünvanlar Tıp Doktoru: 2000 Araştırma Görevlisi Dr: Ankara Üniversitesi Tıp Fakültesi, Farmakoloji ve Klinik Farmakoloji Anabilim Dalı, Farmakoloji Uzmanı: 2006 Doktora Sonrası Araştırmacı: Ruprecht-Karls-Heidelberg Üniversitesi, Tıp Fakültesi Medikal Klinik VII, Almanya Akciğer Hastalıkları Araştırma Merkezi (DLZ-TLRC-H) Heidelberg, Almanya, Yönetilen Yüksek Lisans ve Doktora Tezleri 6.1 Yüksek Lisans Tezleri 6.2 Doktora Tezleri 7. Yayınlar 7.1 Uluslararası hakemli dergilerde yayınlanan makaleler 1. Baloğlu, E., Reingruber T., Bärtsch, P., Mairbäurl,H. β2-adrenergics in hypoxia desensitize receptors but blunt inhibition of reabsorption in rat lung. Am J Respir Cell Mol Biol. 2011; 45 (5): pp Loeh, B., Baloğlu, E., Ke, A., Bartsch, P., Mairbaurl, H. β 2 -adrenergic stimulation blunts inhibition of epithelial ion transport by hypoxia of rat alveolar epithelial cells. Cell Physiol Biochem. 2010; 5(1): Epub 2009 Dec 22. 1

2 3. Baloğlu, E., Ke, A., Abu-Taha, I.H., Bartsch, P., Mairbaurl, H. In vitro hypoxia inhibits β2 adrenergic receptor signaling in primary rat lung alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol Mar; 296 (3):L Güney, S., Schuler, A., Ott, A., Hoschele, S., Baloğlu, E., Bartsch, P., Mairbaurl, H. Dexamethasone prevents transport inhibition by hypoxia in rat lung and alveolar epithelial cells by stimulating activity and expression of Na/K-ATPase and ENaC. Am J Physiol Lung Cell Mol Physiol. 2007; 293 (5):L Baloğlu, E., Kiziltepe, O., Gurdal, H. The role of Gi proteins in reduced vasorelaxation response to β adrenergic receptor agonist in rat thoracic aorta during maturation. Eur J Pharmacol. 2007; 564 (1-3): Uluslararası bilimsel toplantılarda sunulan sözlü sunumlar ve bildiri kitabında (Proceedings) basılan bildiriler Sözlü sunumlar 1. H. Mairbaurl, E. Baloglu, Y. Zhang. Hypoxia prevents the mitochondrial oxygen consumption induced by stimulation of AMPK in cardiomyocytes 92th Annual Meeting of the German Physiological Society, Mart 2-5, 2013, Heidelberg, Almanya. 2. E. Baloglu, H. Mairbaurl. Mechanisms of LPS induced impairment of alveolar Natransport by stimulated macrophages and effects of hypoxia. Turkish-FEBS Physiology Congress, Workshop I, Lung, Macrophages, Hypoxia and Inflammation, Eylül 3-7, İstanbul, Türkiye, E. Baloglu, H. Mairbaurl. Handling cells in hypoxia. Turkish-FEBS Physiology Congress, Workshop I, Lung, Macrophages, Hypoxia and Inflammation, Eylül 3-7, İstanbul, Türkiye, E. Baloglu, H. Mairbaurl. Endotoxin and hypoxia increase the expression of proinflammatory cytokines from alveolar macrophages, ATII cells, and endothelial cells in-vitro. Turkish-FEBS Physiology Congress, Workshop I, Lung, Macrophages, Hypoxia and Inflammation, Eylül 3-7, İstanbul, Türkiye, E. Baloglu, N. Yazihan, P. Bartsch, H. Mairbaurl. Effects of endotoxin and hypoxia on the expression of pro-inflammatory cytokines in lung macrophages, epithelial and endothelial cells and on ion transport in vitro. Joint Meeting of German and Scandinavian Physiological Societies, Kopenhag, Danimarka, Mart 27-30, E. Baloglu, B. Loeh, P. Bartsch, H. Mairbaurl.Hypoxia impairs beta 2 adrenergic signaling and stimulation of alveolar reabsorption in rat alveolar epithelial cells. European Respiratory Society Meeting, Viyana, Avusturya, Eylül 12-16, E. Baloglu, A. Ke, P. Bartsch, H. Mairbaurl. Pertussis toxin prevents hypoxia-induced impairment of β2-adrenergic signaling in primary rat alveolar epithelial cells. 87 th Annual Meeting of the German Physiological Society, Köln, Almanya, Mart 2-5,

3 Basılı bildiriler (Proceedings) 1. E. Baloğlu, K.Velineni, H. Mairbaeurl. HIF-2α is involved in the decreased activitiy of ENaC in hypoxic alveolar epithelial cells. 93th Annual Meeting of German Physiological Society, Mart 13-15, 2014, Mainz, Almanya, Acta Physiologica, March 2014, Volume 210, Supplement 695, E. Baloğlu, K.Velineni, H. Mairbaeurl. Hypoxia decrease Na/K-ATPase transcription and activity by HIF dependent manner. 93th Annual Meeting of German Physiological Society, Mart 13-15, 2014, Mainz, Almanya, Acta Physiologica, March 2014, Volume 210, Supplement 695, K.Velineni, E. Baloğlu, H. Mairbaeurl. Role of HIF in the inflammatory response at the alveolar epithelium and macrophages. 93th Annual Meeting of German Physiological Society, Mart 13-15, 2014, Mainz, Almanya, Acta Physiologica, March 2014, Volume 210, Supplement 695, E. Baloğlu, L. Berg, K.Velineni, H. Mairbäurl. Increased HIF does not cause inhibition of alveolar epithelial ion transport in hypoxia. 92th Annual Meeting of German Physiological Society, Mart 2-5, 2013, Heidelberg, Almanya, Acta Physiologica, March 2013, Volume 207, Supplement 694, K.Velineni, E. Baloğlu, H. Mairbäurl. HIF-1α enhances the enhanced inflamatory response at the alveolar epithelium induced by stimulated macrophages. 92th Annual Meeting of German Physiological Society, Mart 2-5, 2013, Heidelberg, Almanya, Acta Physiologica, March 2013, Volume 207, Supplement 694, E. Baloğlu, T. Reingruber, P. Bartsch, H. Mairbaurl. In-vivo Hypoxia and terbutalinetreatment impairs beta-2-adrenergic signalling in ATII cells but blunts hypoxic inhibition of alveolar reabsorption. American Thoracic Society Meeting, Mayis 14-19, 2010, New Orleans, Louisiana, ABD Am J Respir Crit Care Med 181;2010:A E. Baloğlu, N. Yazıhan, P. Bärtsch, H. Mairbäurl. Endotoxin but not hypoxia increases the expression of pro-inflammatory cytokines from alveolar macrophages, ATII and endothelial cells in an in-vitro model of the alveolar barrier. American Thoracic Society Meeting, Mayis 14-19, 2010, New Orleans, Louisiana, ABD. Am J Respir Crit Care Med 181;2010:A E. Baloğlu, T. Reingruber, P. Bartsch, H. Mairbaurl. Prolonged treatment with terbutaline blunts hypoxic inhibition of alveolar reabsorption in-vivo. Joint Meeting of German and Scandinavian Physiological Societies, Mart 27-30, 2010, Kopenhag, Danimarka Acta Physiologica (2010); 198: Suppl 677, March. 9. E. Baloğlu, A. Ke, P. Bartsch, H. Mairbaurl. Hypoxia impairs β2-adrenergic receptor signaling through pertussis toxin sensitive mechanisms in rat primary alveolar cells. XXXVIII International Congress of Physiological Science and Experimental Biology Meeting, Nisan 5-9, 2008, San Diego, Kaliforniya, ABD. FASEB J 2008;22: E. Baloğlu, A. Ke, P. Bartsch, H. Mairbaurl. Pertussis toxin prevents hypoxia-induced impairment of beta2-adrenergic signaling in primary rat alveolar epithelial cells 87 th Annual Meeting of the German Physiological Society, Mart 2-5, 2008, Köln, Almanya Acta 3

4 Physiologica (2008); 192:89-89 Suppl. 663, March. 11. E. Baloğlu ve H. Gürdal. Chronic treatment with beta-adrenergic receptor antagonists restores impaired beta-adrenergic receptor mediated responses during maturation and aging in rat aorta. Experimental Biology Meeting, Mart 31-Nisan 5, 2005, San Diego, Kaliforniya, ABD, FASEB J 2005; 19 (4): A107-A107 Part 1 Suppl. S MAR F. Ademoğlu, N. Abacıoğlu, E. Baloğlu, H. Gürdal. The Effect of Ghrelin on Adenylyl Cyclase and PL-C Activity in Rat Aorta. 4 th European Meeting on Vascular Biology and Medicine, Eylül 28-30, Hamburg, Almanya, J of Vasc Res Sept (42), suppl II/ :328. Basılmamış kongre bildirileri 1. E. Baloglu, L. Berg, K. Velineni, Mairbaeurl. Increased HIF does not cause inhibition of alveolar epithelial ion transport in hypoxia. Oxygen 2013, Dealing with hypoxia: Regulatory aspects in cells, tissues and organisms, Haziran 8-12, 2013, Oulu, Finlandiya. 2. E. Baloğlu, G. Nonnenmacher, P. Bartsch, H. Mairbaurl. HIF is required to maintain alveolar epithelial cell function in hypoxia. Keystone Symposia, Advances in Hypoxic Signaling: From Bench to Bedside, Şubat 12-17, 2012, Banff, Alberta, Kanada. 3. Y. Zhang, E. Baloğlu, P. Bartsch, H. Mairbaurl. Increase in cell metabolism by stimulation of AMPK and ERRa in cardiomyocytes is abolished by hypoxia. Keystone Symposia, Advances in Hypoxic Signaling: From Bench to Bedside, Şubat 12-17, 2012, Banff, Alberta, Kanada 4. E. Baloğlu, G. Nonnenmacher, H. Mairbaurl. Beta 2 adrenergic stimulation increases the expression of HIF-1α and HIF-2α. HypoxiaNet, Sensing Hypoxia in the Cell and the Organism, Eylül 20-23, 2012, Essen, Almanya. 5. E. Baloğlu, G. Nonnenmacher, H. Mairbaurl. Beta 2 adrenergic stimulation increases the expression of HIF-1α and HIF-2α. 91th Annual Meeting of German Physiological Society, Mart 22-25, 2012, Dresden, Almanya 6. E. Baloglu, B. Loeh, A. Ke, I. Abu-Taha, P. Bartsch, H. Mairbaurl. Beta 2 adrenergic stimulation blunts hypoxic inhibition of alveola epithelial reabsroption despite impaired, Gi protein dependent inhibition of signaling in rat alveolar epithelial cells. Pulomonet Congress 2009, Mart , Insbruck, Tyrol, Avusturya. 7. E. Baloğlu, A. Ke, P. Bartsch, H. Mairbaurl. Hypoxia impairs beta2 adrenergic receptor signaling in rat primary alveolar cells by pertussis toxin sensitive mechanisms. Pulmonet International Meeting Secretion and Transport in Normal and Diseased Pulmonary Epithelia, Mart 10-11, Saarbruecken, Almanya 4

5 7.3 Yazılan uluslararası kitaplar veya kitaplarda bölümler 7.4 Ulusal hakemli dergilerde yayınlanan makaleler 1. Cengiz, AT., Kiyan, M., Tibet, M., Bingöl, M., Tural, T., Baloğlu, E., Çapka, DU. Sağlikli Bireylerin Serumlarinda Cytomegalovirus (CMV) IgG Antikorlarinin ELISA yöntemiyle arastirilmasi. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 49 (1), Ulusal bilimsel toplantılarda sunulan ve bildiri kitabında basılan bildiriler Ulusal Sözlü Sunumlar 1. E. Baloğlu ve Hakan Gürdal. Sıçan damar düz kasinda yas artışı ve maturasyon boyunca beta adrenerjik reseptör yanıtlarında pertussis toxin sensitif G proteinlerinin rölü. 18. Ulusal Türk Farmakoloji Derneği Kongresi, 28 Eylül-1 Ekim, 2005, İzmir, Türkiye. 7.6 Diğer yayınlar 8. Projeler 1. Yardımcı Araştırmacı: Effects of hypoxia on beta-2 adrenergic signaling in lung alveolar epithelium, Almanya-DFG (Deutsche Forschung Gemainschaft), Ma 1503/18-1, 2,3, Kasım 2006-Ocak 2008 (Tamamlandı) 2.Yardımcı Araştırmacı: Hormonal stimulation of shark rectal gland secretion in hypoxia, Mount Desert Island Biological Laboratory New Investigator Award, Main, USA ve Almanya-DFG (Deutsche Forschung Gemainschaft) Ma 1503/24-1 2/8-7/9/2008 (Tamamlandı) 3. Proje yürütücüsü, yardımcı arastırmacı: Role of hypoxia inflammation, and betaadrenergic signaling on activity and expression of ion transporters in primary alveolar epithelial cells, Almanya-DFG (Deutsche Forschung Gemainschaft), Ma-1503/28-1, Nisan 2011-Mayıs 2014 (Tamamlandı) 9. İdari Görevler 10. Bilimsel Kuruluşlara Üyelikler 11. Ödüller 1. Araştırma ve Kongre Destek Ödülü: Heidelberg Üniversitesi Tıp Fakültesi, Graduiertenakademie, Araştırma ve Kongre Destek Ödülü: Heidelberg Üniversitesi Tıp Fakültesi Graduiertenakademie,

6 12. Son iki yılda verdiğiniz lisans ve lisansüstü düzeydeki dersler için aşağıdaki tabloyu doldurunuz. Akademik Yıl Dönem Dersin Adı Haftalık Saati Teorik Uygulama Öğrenci Sayısı Not: Açılmışsa, yaz döneminde verilen dersler de tabloya ilave edilecektir. 6