I A JOURNAL OF N O I T A o f H EALTH I N V E S T I G CLINICAL AND C T SO S A IO N S EXPERIMENTAL INVESTIGATIONS eissn 1309-6621 Volume 7 Issue 1 March 2016 Citation Abbreviation: J Clin Exp Invest Publishes four times a year Open access: www.jceionline.org
JOURNAL OF CLINICAL AND EXPERIMENTAL INVESTIGATIONS eissn 1309-6621 Editor-in-Chief Aydın Ece, MD, Prof., Department of Pediatrics, School of Medicine, Dicle University, Turkey İ. Hamdi Kara, MD, Prof., Department of Family Medicine, School of Medicine, Duzce University, Turkey Executive Editors Harun Yüksel, MD, PhD, Assoc. Prof., Department of Ophthalmology, School of Medicine, Dicle University, Turkey Metin Aytekin, PhD, Assoc. Prof., Department of Medical Biology, School of Medicine, Erciyes University, Turkey Alparslan Şahin, MD, PhD, Assoc. Prof., Department of Ophthalmology, School of Medicine, Dicle University, Turkey INTERNATIONAL EDITORIAL BOARD Salih Kavukçu, MD, Prof., Department of Pediatrics, School of Medicine, Dokuz Eylul University, Turkey Kadri Altundağ, MD, Prof., Department of Medical Oncology, School of Medicine, Hacettepe University, Turkey Kahharov J. Nematovich, MD, Prof., Tashkent Medical Academy, Department of Surgery and Oncology, Tashkent- Uzbekistan Abdulsattar Khan, MD, Assist. Prof., Khan King Faisal University Medical Faculty, Department of Family Medicine- Saudi Arabia Muharem Zildzic, MD, Prof., Academy of Science and Arts, Department of Medical Sciences, Sarajevo, Bosnia and Herzegovina Leonas Valius, MD, Prof., Kaunas University of Medicine, Department of Family Medicine- Lithuania Bakir Mehić, MD, Prof., University of Sarajevo, Sarajevo - Bosnia and Herzegovina Kemal S. Akbarov, MD, National Center of Oncology, Department of Radiotherapy, Baku - Azerbaijan Ibragimov S. Narzikulovich, MD, Scientific Head of the Department Radiotherapy and Radiology, ROSC - Uzbekistan Zaim Jatic, MD, Assist. Prof., Sarajevo University Medical Faculty, Department of Family Medicine - Bosnia & Herzegovina Reşat Özaras, MD, Prof., Department of Infectious Diseases, School of Medicine, İstanbul University, Turkey M. Faruk Geyik, MD, Prof., Department of Infectious Diseases, School of Medicine, Duzce University, Turkey Boris Itkin, MD, Medico Oncologo en Juan Fernandez General Hospital, Buenos Aires - Argentina Ksenija Tušek-Bunc, MD, Assist. Prof., University of Maribor and Ljubljana Medical School, Family Medicine - Slovania Anake Kijjoa, PhD, Prof., Chemistry of the Biomedical Sciences Institute of Abel Salazar (ICBAS), University of Porto, Portugal Carmen Busneag, MD, Assoc. Prof., Spiru Haret University, Family Medicine Office - Romania Contact Person Prof.Dr. Aydın Ece, Dicle University Medical Faculty Department of Pediatrics, Diyarbakır - Turkey Phone: +90-412 248 80 01 / 4737-5784 ; Fax: +90-412- 248 84 40 Email: jcei@jceionline.org Web Address: www.jceionline.org Journal of Clinical and Experimental Investigations (JCEI) is a peer-reviewed medical journal and published four times a year (March, June, September and December). JCEI is abstracted/indexed in EBSCO, DOAJ, CrossRef, Index Copernicus, Google Scholar, TUBITAK ULAKBIM, Turkey Citation Index and Turk Medline Copyright Journal of Clinical and Experimental Investigations 2016, All rights reserved Publishing Date: March 2016 Address for requests: Prof.Dr. Aydın Ece, Dicle University Medical Faculty Department of Pediatrics, 21280 Diyarbakır - Türkiye MMEDİSAN Typesetting Medisan Yayınevi Ltd.Şti. Çankırı Cad. 45/347 Ulus-Ankara, Turkey Tel : (+90 312) 311 24 26 311 00 57 Email: medisanyayinevi@gmail.com
JCEI- Instructions for Authors V INSTRUCTIONS FOR AUTHORS All manuscripts should be prepared as appropriate for Uniform Requirements for manuscripts submitted to Biomedical Journals (http://www.icmje.org). All submitted manuscripts must be contributed solely to Journal of Clinical and Experimental Investigations not be under consideration for publication elsewhere. A copyright transfer statement must be signed by all authors and Conflict of Interest Form should accompany each submission. Ethical considerations Manuscripts submitted for publication must contain a statement indicated that all prospective human studies have been approved by the ethics Committee, have therefore been performed in accordance with the ethical standards of 2013 Declaration of Helsinki. It should also be clearly stated that all persons gave informed consent prior to their inclusion in the study. Studies involving animals must have the animal ethics committee approval and be conducted in accordance with the care and use of laboratory animals standards. Copyright agreement All submitted materials become the property of Journal of Clinical and Experimental Investigations. If a submission is accepted for publication, authors will sign a copyright transfer agreement. Copyright transfer agreement signed by all authors or by the correspondent Author on behalf of all authors should be sent to the Journal in a PDF file during the first submission process. The publisher reserves the copyright. Materials published in Journal of Clinical and Experimental Investigations may not be reproduced or published elsewhere without written permission of the Publisher. The journal allow the author(s) to hold the copyright and to retain publishing rights without restrictions. Manuscript preparation Manuscripts should be arranged in the following order; Title page, Abstracts, Key words, Introduction, Materials and Methods, Results, Discussion, Acknowledgements, References, Tables, Figure Legends, Figures. All of these sections should run consecutively. The use of subheads is encouraged. Journal of Clinical and Experimental Investigations will consider the publication of manuscripts dealing with clinical or laboratory investigations, including original investigations, case reports, invited reviews and letter to editors in the broad field of Medicine. Animal or in vitro research will also be considered. All manuscripts are subject to peer-review. Manuscripts should be written in English. Title page: The title page should not contain abbreviations. The title page should contain the full names and affiliations of all authors, Conflict of Interest statement and complete contact information (including address, phone number, fax number, email) of the corresponding author. Abstract: An abstract of no more than 250 words in length, describing the aims, the results that were obtained from presented data and the conclusions. Abstract should be written in a structured manner including Objectives, Materials and methods, Results and Conclusions subheadings. Key words: Up to five key words should be supplied following the abstract. The key words should reflect the central topic of the article and should be in compatible with Medical Subject Headings (MeSH). References: References should be numbered consecutively in order of their appearance in the text and listed in numerical order. References should be given within bracket parenthesis throughout main text of the manuscript such as [15]. Journal titles should be abbreviated according to Index Medicus. The name of all authors should be written in the References, if six or less authors exist, and the first three authors and et al. should be given if the number of authors exceeds six. References with correct punctuation should be as follows: Journals - Anderson NJ, Abbott GD, Mogridge N, Allan RB, Maling TM, Wells E. Vesicoureteric reflux in the newborn: relationship to fetal renal pelvic diameter. Pediatr Nephrol 1997;11:610-616. - Dunne FP, Elliot P, Gammage MD, et al. Cardiovascular function and glucocorticoid replacement in patients with hypopituitarism. Clin Endocrinol 1995;43:629-632. Books - Hatch DJ, Sumner E, Hellman J. The Surgical Neonate: Anaesthesia and Intensive Care, 3 rd edn. London: Edward Arnold, 1994:120-5. Chapter in a book: Motoyama EK. Respiratory physiology in infants and children. In: Motoyama EK, Davis PJ, eds. Smith s Anesthesia for In- J Clin Exp Invest www.jceionline.org Vol 7, No 1, March 2016
VI JCEI- Instructions for Authors fants and Children, 5 th edn. St. Louis: C.V. Mosby, 1990:11-76. A paper published online but not (yet) in print can be cited using the Digital Object Identifier (DOI). Tables and illustrations: Tables must be self explanatory and must not duplicate information in the text. Each table must have a title and should be numbered in order of appearance in the text. Any symbol and abbreviations used in the table body must be defined in a footnote to the table. Title page should be prepared as separate Word file, and Abstract, Main text, References, Tables and Figure legends should be incorporated in one document file and submitted as a single file. Pictures and figures should be submitted as separate JPG files for each picture and figure. Copyright Transfer Agreement Form should be signed by all authors and submitted together with Manuscript files. All manuscripts should be submitted by online submission using Autor Login of Online Submission at jcei@jceionline.org. If you have any question please contact us via jcei@jceionline.org email address. If authors submit a complaint this complaint will be assessed and finalized by Editors in Chief. J Clin Exp Invest www.jceionline.org Vol 7, No 1, March 2016
CONTENTS VII RESEARCH ARTICLE Changing of Uric Acid Levels by Age and Sex in Patients with Diabetes Mellitus Diyabetes Mellitus lu Hastalarda Ürik Asit Seviyelerinin Yaş ve Cinsiyetle Değişimi Nilgün Basaran, Osman Evliyaoglu, Veysel Sucu, Okan Dikker, Leyla Bulut, Fatma Tezcan, Vesile Kalaslıoğlu, Rıza Sandıkçı, Müberra Vardar...1 Laparoscopic Uterine Nerve Ethanol Neurolysis (LUNEN) in Patients with Chronic Pelvic Pain Kronik Pelvik Ağrılı Hastalarda Laparoskopik Uterin Sinir Etanol Nörolizisi (LUNEN) Seyhan Sönmez, Ümit Naykı, Paşa Uluğ, Cenk Naykı, Ferhan Sönmez, Şivekar Tınar, Yusuf Yıldırım...7 A Single Center Experience on the Management of Placental Invasion Abnormalities Tek Bir Merkezin Plasental İnvazyon Anomalilerinin Yönetimindeki Deneyimi Alper Biler, Atalay Ekin, Cenk Gezer, Ulaş Solmaz, Nuri Peker, Aykut Özcan, Mehmet Özeren... 14 Crystallized Phenol Treatment in Postoperative Recurrent Pilonidal Disease Cerrahi Sonrası Nüks Pilonidal Sinüs Hastalığında Kristalize Fenol Tedavisi Zülfü Bayhan, Sezgin Zeren, Şükrü Aydın Düzgün... 19 Clinical Approach to Patients with Mastalgia in Breast Disease Outpatient Clinic Meme Hastalıkları Polikliniğine Mastalji Nedeni ile Başvuran Hastalara Klinik Yaklaşım Sezgin Zeren, Zülfü Bayhan, Cengiz Koçak... 23 Anticoagulant Therapy in Primary and Secondary Recurrent Pregnancy Losses with Hereditary Thrombophilia and Perinatal Outcomes Kalıtsal Trombofilili Primer ve Sekonder Tekrarlayan Gebelik Kayıplarında Antikoagulan Tedavi ve Gebelik Sonuçları Hatice Işık, Hüsnü Alptekin, Refika Selimoglu, Türkan Cengiz, Hasibe Uygun Küçükapan, Nazife Alptekin... 29 Are Pediatric Emergency Care Applied Research Network Rules (PECARN) Sufficient for Computed Cranial Tomography Decision in Pediatric Patients with Mild Head Trauma? Hafif Kafa Travmalı Pediyatrik Hastalarda Bilgisayarlı Beyin Tomografisi Kararı İçin PECARN Kuralları Yeterli midir? Hasan Mansur Durgun, Erkan Tektas, Yılmaz Zengin, Recep Dursun, Mustafa İçer, Mehmet Ustundag, Murat Orak, Cahfer Guloglu... 35 Assessment of Quality of Life, Psychological and Functional Status and Disease Activity in Patients with Ankylosing Spondylitis and Fibromyalgia Ankilozan spondilit ve Fibromiyaljili Hastalarda Hastalık Aktivitesi, Hayat Kalitesi ve Psikolojik ve Fonksiyonel Durumun Değerlendirilmesi Mehmet Caglayan, Mehmet Günes, Mehtap Bozkurt, Kemal Nas. 41 Periton Diyalizi Hastalarında Homosistein Düzeylerindeki Artışın Ateroskleroza Etkisi The Effect of Elevated Homocysteine Levels on Atherosclerosis in Patients with Peritoneal Dialysis Fatih Şahpaz... 47 Katarakt Ameliyatı Esnasında Uygulanan Terapötik Dokunmanın Kaygı ve Hasta Memnuniyetine Etkisi The Effect of Therapeutic Touch Performed During Cataract Surgery on Anxiety and Patient Satisfaction Emel Yılmaz, Zeliha Birer, Hakan Baydur... 52 Romatoid Artritli Hastalarda İşitme Fonksiyonlarının Odyolojik Testlerle Değerlendirilmesi Evaluation of Hearing Functions with Audiological Tests in Patients with Rheumatoid Arthritis Selma Evran Uzun, Adem Yıldırım, Sedat Doğan, Gülseren Dost Sürücü, Mehmet Karabiber, Yasin Sarıkaya... 63 Doğurganlık Yaşındaki Kadınlarda Hepatit E Virus IgG Seroprevalansının Araştırılması Investigation of Hepatitis E Virus IgG Seroprevalence in Women of Reproductive Age Erdal Özbek, Hakan Temiz, Ayşe Batgi Azarkan, Mehmet Obut, Şeyhmus Mete... 69 Kronik Venöz Yetmezlikli Hastalarda Ortalama Trombosit Hacmi Mean Platelet Volume in Patients with Chronic Venous Insufficiency Mehmet Akif Sarıca, Betül Kızıldağ, Mustafa Yavuz Selçuk, Ayşe şahin Tutak, Ali Haydar Baykan, Hacı Taner Bulut, İbrahim Halil Türkbeyler... 73 Cinsiyet, Yaş ve Kırma Kusurunun Kornea ve Konjonktivanın Epitel ve Tüm Kalınlığı Üzerine Etkileri The Effects of Gender, Age, and Refractive Error on Corneal and Conjunctival Epithelial and Overall Thicknesses İsmail Erşan, Selçuk Kara, Sedat Arıkan, Baran Gencer, Hasan Ali Tufan... 78 Nazofarenks Patolojilerinde Punch Biyopsi Sonuçları Punch Biopsy Results of Nasopharynx Pathologies İsa Özbay, Cüneyt Kucur, Sinan Aksoy, Fatih Oghan, Semra Külekçi, Nadir Yıldırım... 83 CASE REPORT A Rare Cause of Abdominal Mass: Rapunzel Syndrome Karında Kitlenin Nadir Bir Sebebi: Rapunzel Sendromu Feyzullah Uçmak, Remzi Beştaş, Haydar Adanır, Nazım Ekin, Ali Tardu... 87 Three Cases of Adenomyoepithelioma: An Unusual Breast Neoplasm Üç Adenomiyoepitelyoma Olgusu: Nadir Bir Meme Tümörü Murat Özgür Kılıç, Meral Sen, Cenap Dener, Dilek Kösehan, Sibel Yenidünya... 91 J Clin Exp Invest www.jceionline.org Vol 7, No 1, March 2016
VIII CONTENTS Bietti Crystalline Retinal Dystrophy: A Case Report Bietti Kristalin Retinal Distrofi: Olgu Sunumu Muhammed Şahin, Adnan Yıldırım, Fatih Mehmet Türkcü, Harun Yüksel, Alparslan Şahin... 94 Pulmonary Nodulosis Associated with Leflunomide Therapy in Rheumatoid Arthritis: Report of Four Cases and Review of the Literature Romatoid Artitte Leflunomid Tedavisi ile İlişkili Pulmoner Nodülozis: 4 Vaka Sunumu ve Literatürün Gözden Geçirilmesi Ayse Balkarli, Veli Cobankara... 98 Early Development of Slipped Capital Femoral Epiphysis in a Patient with Infantile Tibia Vara İnfantil Tibia Varalı Bir Hastada Erken Gelişen Femur Başı Epifizi Kayması Hristo Georgiev, Georgi P. Georgiev, Milka Dikova...103 Benign Endometrial Polip ve Polibe Sınırlı Primer Endometrial Küçük Hücreli Nöroendokrin Karsinom: Nadir bir Birliktelik Benign Endometrial Polyp and Primary Endometrial Small Cell Neuroendocrine Carcinoma Confined to the Polyp: A Rare Association Pembe Oltulu, Ceyhan Uğurluoğlu, Ayşenur Uğur, Sıdıka Fındık, Lema Tavlı...106 REVIEW ARTICLE Helsinki Bildirgesi nin Biyoetik ve Biyopolitikalar Bağlamında İzini Sürmek In the Context of Bioethics and Biopolitics with Keeping Track of the Helsinki Declaration Ümit Yaşar Öztoprak, Mesut Ersoy, Onur Naci Karahancı, Nüket Örnek Büken...110 Gebelikte Tiroid Hastalıkları ve Tedavisi Thyroid Diseases and Treatment in Pregnancy Aynur Aktaş, Zafer Pekkolay...119 J Clin Exp Invest www.jceionline.org Vol 7, No 1, March 2016