ÜYE OLDUĞU BİLİMSEL DERNEKLER

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1 ÖZGEÇMİŞ Doç. Dr. Alptekin GÜRSOY Doğum Tarihi: 26 Kasım 1971 Doğum Yeri: Ordu Ordu İstiklal İlkokulu ve Ordu Lisesi nden mezun oldu yılında Hacettepe Üniversitesi Tıp Fakültesi (ingilizce) ni bitirdi yılları arasında Ankara Tıp Fakültesi İç Hastalıkları Ana Bilim Dalı nda uzmanlık ihtisasını tamamladı yılında Almanya Hamburg şehrinde Institute For Hormone and Fertility Research merkezinde misafir bilim adamı olarak çalıştı yılları arasında Ankara Üniversitesi Tıp Fakültesi İç Hastalıkları Ana Bilim Dalı Endokrinoloji ve Metabolizma Hastalıkları Bilim Dalı nda yan dal uzmanlık eğitimi alarak Endokrinoloji ve Metabolizma Hastalıkları uzmanı oldu yılları arasında Başkent Üniversitesi Tıp Fakültesi Endokrinoloji ve Metabolizma Hastalıkları Bilim Dalı nda görev yaptı yılında Doçent oldu Halen tam zamanlı olarak Ankara Güven Hastanesi Endokrinoloji ve Metabolizma Hastalıkları Bölümü nde çalışmaktadır ÜYE OLDUĞU BİLİMSEL DERNEKLER Türkiye Endokrinoloji ve Metabolizma Derneği (TEMD) European Society of Endocrinology (ESE) European Thyroid Association (ETA) Türkiye İç Hastalıkları Uzmanlık Derneği (TİHUD) Ankara Tabip Odası (ATO) İLGİ ALANI A. Klinik Tiroid hastalıkları Tiroid nodülleri ve tiroid kanserleri takip ve tedavi Tiroid ultrasonografi Tiroid ince iğne aspirasyon biyopsisi Multipl endokrin neoplazi tip 2 sendromlarında ret proto-onkogen mutasyonu

2 Otoimmün tiroid hastalıkları Diabetes mellitus ve komplikasyonları Genel endokrinoloji B. Araştırma Tiroid nodülleri ve tiroid kanserleri Tiroid ultrasonografi ve tiroid ince iğne aspirasyon biyopsisi Multipl endokrin neoplazi tip 2 sendromlarında ret proto-onkogen mutasyonu Otoimmün tiroid hastalıkları Uluslararası hakemli dergilerde yayınlanan makaleler (h-index: 25) 1- Soylu L, Aydin OU, Ozbas S, Bilezikci B, Ilgan S, Gursoy A, Kocak S. The impact of the multifocality and subtypes of papillary thyroid carcinoma on central compartment lymph node metastasis. Eur Rev Med Pharmacol Sci Oct;20(19): Aydin OU, Soylu L, Ozbas S, Ilgan S, Bilezikci B, Gursoy A, Sengezer T, Kocak S. Eur Rev Med Pharmacol Sci May;20(9): The risk of hypoparathyroidism after central compartment lymph node dissection in the surgical treatment of pt1, N0 thyroid papillary carcinoma. 3- Aydoğan Bİ, Yüksel B, Tuna MM, Navdar Başaran M, Akkurt Kocaeli A, Ertörer ME, Aydın K, Güldiken S, Şimşek Y, Cihan Karaca Z, Yılmaz M, Aktürk M, Anaforoğlu İ, Kebapçı N, Duran C, Taşlıpınar A, Kulaksızoğlu M, Gürsoy A, Dağdelen S, Erdoğan MF. Distribution of RET Mutations and Evaluation of Treatment Approaches in Hereditary Medullary Thyroid Carcinoma in Turkey. J Clin Res Pediatr Endocrinol Mar 5;8(1): doi: /jcrpe Epub 2015 Dec Anil C, Kut A, Atesagaoglu B, Nar A, Bascil Tutuncu N, Gursoy A. Metformin Decreases Thyroid Volume and Nodule Size in Subjects with Insulin Resistance: A Preliminary Study. Med Princ Pract. 2016;25(3): Kut A, Kalli H, Anil C, Mousa U, Gursoy A. Knowledge, attitudes and behaviors

3 of physicians towards thyroid disorders and iodine requirements in pregnancy. J Endocrinol Invest Anil C, Guney T, Gursoy A. The prevalence of benign breast diseases in patients with nodular goiter and Hashimoto's thyroiditis. J Endocrinol Invest Duran AO, Anil C, Gursoy A, Nar A, Inanc M, Bozkurt O, Tutuncu NB. Thyroid volume in patients with glucose metabolism disorders. Arq Bras Endocrinol Metabol Ilgan S, Ozbas S, Bilezikci B, Sengezer T, Aydin OU, Gursoy A, Kocak S. Radioguided occult lesion localization for minimally invasive parathyroidectomy: technical consideration and feasibility. Nucl Med Commun Duran AO, Anil C, Gursoy A, Nar A, Altundag O, Inanc M, Bozkurt O, Tutuncu NB. The relationship between thyroid volume and malignant thyroid disease. Med Oncol Anil C, Akkurt A, Ayturk S, Kut A, Gursoy A. Impaired glucose metabolism is a risk factor for increased thyroid volume and nodule prevalence in a mild-tomoderate iodine deficient area. Metabolism Duran AO, Anil C, Gursoy A, Nar A, Altundag O, Tutuncu NB. The relationship between glucose metabolism disorders and malignant thyroid disease. Int J Clin Oncol Mousa U, Gursoy A, Ozdemir H, Moray G. Medullary thyroid carcinoma in a patient with Hashimoto's thyroiditis diagnosed by calcitonin washout from a thyroid nodule. Diagn Cytopathol Küpeli E, Ulubay G, Ulasli SS, Sahin T, Erayman Z, Gürsoy A. Metabolic syndrome is associated with increased risk of acute exacerbation of COPD: a preliminary study. Endocrine Gursoy A., Anil C., Erismis B., Ayturk S. Fine needle aspiration biopsy of a thyroid nodule: A comparison of diagnostic performance of experienced and inexperienced physicians. Endocrine Practice 2010.

4 15- Gursoy A. Rising thyroid cancer incidence in the world might be related to insulin resistance. Medical Hypotheses Ayturk S., Gursoy A., Kut A., Anil C., Nar A., Tutuncu N.B. Metabolic syndrome and its components are associated with increased thyroid volume and nodule prevalence in a mild-to-moderate iodine-deficient area. European Journal of Endocrinology Anil C, Goksel S, Gursoy A. Hashimoto's Thyroiditis Is Not Associated with Increased Risk of Thyroid Cancer in Patients with Thyroid Nodules: A Single- Center Prospective Study. Thyroid Kut A, Gursoy A, Senbayram S, Bayraktar N, Budakoglu II, Akgun HS. Iodine intake is still inadequate among pregnant women eight years after mandatory iodination of salt in Turkey. Journal of Endocrinological Investigation Torun A.N., Gursoy A., Tutuncu N.B., Demirag N.G. Familial thrombocytopenia associated with ovarian agenesis, umbilical hernia, bicuspid aortic valve, patent ductus arteriosus and epilepsia. Turkish Journal of Hematology Sahin M., Sade L.E., Tutuncu N.B., Gursoy A., Kabapcilar L., Muderrisoglu H., Guvener N.D. Systolic pulmonary artery pressure and echocardiographic measurements in patients with euthyroid Hashimoto's thyroiditis. Journal of Endocrinological Investigation Nar Demirer A., Ayturk S., Tutuncu N.B., Gursoy A., Pak Y., Demirag N.G. Systolic pulmonary artery pressure and echocardiographic measurements in patients with euthyroid Hashimoto's thyroiditis. Experimental and Clinical Endocrinology and Diabetes Sahin M., Gursoy A., Erdogan M.F. Cytotoxic T lymphocyte-associated molecule- 4 polymorphism in Turkish patients with Hashimoto thyroiditis. International Journal of Immunogenetics Sahin M., Gursoy A., Erdogan M.F. Cytotoxic T lymphocyte-associated molecule- 4 polymorphism in Turkish patients with Hashimoto thyroiditis. Genetic Testing 2009.

5 24- Gursoy A., Anil C., Tutuncu N.B., Nar A., Ayturk S.Comparison of the analgesic efficacy of lidocaine/prilocaine (EMLA) cream and needle-free delivery of lidocaine during fine-needle aspiration biopsy of thyroid nodules. Turkish Journal of Endocrinology and Metabolism Cin M.O., Gursoy A., Morris Y., Aydintug O.T., Kamel N., Gullu S.Prevalence and clinical significance of antineutrophil cytoplasmic antibody in Graves' patients treated with propylthiouracil. International Journal of Clinical Practice Uysal A.R., Sahin M., Gursoy A., Gullu S. Vitamin D receptor gene polymorphism and osteoporosis in the Turkish population. Genetic Testing Gursoy A., Anil C., Unal A.D., Demirer A.N., Tutuncu N.B., Erdogan M.F. Clinical and epidemiological characteristics of thyroid hemiagenesis: ultrasound screening in patients with thyroid disease and normal population. Endocrine Torun A.N., Kulaksizoglu M., Gursoy A. Visual vignette. Systemic lymphoma presenting with involvement of the thyroid gland and hypothyroidism. Endocrine practice Gursoy A., Tutuncu N.B., Gencoglu A., Anil C., Demirer A.N., Demirag N.G. Radioactive iodine in the treatment of type-2 amiodarone-induced thyrotoxicosis. Journal of the National Medical Association Mustafa Şahin, Aslı Doğruk, Mustafa Kulaksızoğlu, Alptekin Gürsoy, Derun Ertuğrul, Emre Bozkırlı, Hamiyet Yılmaz, Neslihan Tütüncü, Nilgün Demirağ. Subclinical Hypothyroidism is not Associated with Hyperhomocysteinyemia. Turkish Journal of Endocrinology and Metabolism Ertugrul D.T., Gursoy A., Sahin M., Unal A.D., Pamuk B., Berberoglu Z., Ayturk S., Tutuncu N.B., Demirag N.G. Evaluation of brain natriuretic peptide levels in hyperthyroidism and hypothyroidism. Journal of the National Medical Association Demirer A.N., Kemal Y., Gursoy A., Sahin M., Tutuncu N.B. Clinicopathological characteristics of thyroid cancer in patients on dialysis for end-stage renal disease. Thyroid 2008.

6 33- Yilmaz H., Gursoy A., Sahin M., Guvener Demirag N. Acta Diabetologica 2007.Comparison of insulin monotherapy and combination therapy with insulin and metformin or insulin and rosiglitazone or insulin and acarbose in type 2 diabetes. 34- Sahin M., Yilmaz H., Gursoy A., Demirel A.N., Tutuncu N.B., Guvener N.D. Gynaecomastia in a man and hyperoestrogenism in a woman due to ingestion of nettle (Urtica dioica). New Zealand Medical Journal Erdogan M.F., Gursoy A., Gullu S., Aydintug S., Kucuk B., Baskal N., Kamel N., Hoppner W., Erdogan G. Clinical and genetic experience in Turkish multiple endocrine neoplasia type 2 families. Endocrinologist Berberoglu Z., Gursoy A., Bayraktar N., Yazici A.C., Tutuncu N.B., Demirag N.G. Rosiglitazone decreases serum bone-specific alkaline phosphatase activity in postmenopausal diabetic women. Journal of Clinical Endocrinology and Metabolism Torun A.N.I., Gursoy A., Unal A.D., Demirag N.G. Subclinical Cushing syndrome presenting with hypertension and hypokalemia. Endocrinologist Gursoy A., Ertugrul D.T., Sahin M., Tutuncu N.B., Demirer A.N., Demirag N.G. The analgesic efficacy of lidocaine/prilocaine (EMLA) cream during fine-needle aspiration biopsy of thyroid nodules. Clinical Endocrinology Gursoy A., Ertugrul D.T., Sahin M., Tutuncu N.B., Demirer A.N., Demirag N.G. Needle-free delivery of lidocaine for reducing the pain associated with the fineneedle aspiration biopsy of thyroid nodules: Time-saving and efficacious procedure. Thyroid Cesur M., Bayram F., Kamel N., Corapcioglu D., Gursoy A., Gonen S., Ozduman M., Emral R., Uysal A.R., Tonyukuk V., Yilmaz A.E. A comparison of glycemic effects of glimepiride, repaglinide, and insulin glargine in type 2 diabetes mellitus during Ramadan fasting. Diabetes Research and Clinical Practice Gursoy, A., M. F. Erdogan, M. Mine Ozduman Cin, M. Cesur, N. Baskal, Openlabel study for the comparison of metabolic effects of orlistat and sibutramine in women participating in an Obesity management program, Turkish Journal of Endocrinology and Metabolism 2007.

7 42- Gursoy A., Erdogan M.F., Cin M.O., Cesur M., Baskal N. Comparison of orlistat and sibutramine in an obesity management program: Efficacy compliance, and weight regain after noncompliance. Eating and Weight Disorders Erdogan M.F., Gursoy A., Erdogan G. Natural course of benign thyroid nodules in a moderately iodine-deficient area. Clinical Endocrinology Changes in insulin sensitivity and glucose and bone metabolism over time in patients with asymptomatic primary hyperparathyroidism. Ayturk S., Gursoy A., Tutuncu N.B., Ertugrul D.T., Demirag N.G. Journal of Clinical Endocrinology and Metabolism Significance of the RET proto-oncogene polymorphisms in Turkish sporadic medullary thyroid carcinoma patients. Gursoy A., Erdogan M.F., Erdogan G. Journal of Endocrinological Investigation Gursoy A., Ertugrul D.T., Pamuk B., Sahin M., Asik M., Yilmaz H., Haydardedeoglu F., Tutuncu N.B., Demirag N.G. Mean platelet volume in patients with polycystic ovary disease. Platelets Erdogan M.F., Gursoy A., Kulaksizoglu M. Long-term effects of elevated gastrin levels on calcitonin secretion. Journal of Endocrinological Investigation Sahin M., Gursoy A., Tutuncu N.B., Guvener D.N. Prevalence and prediction of malignancy in cytologically indeterminate thyroid nodules. Clinical Endocrinology Cesur M., Gursoy A., Avcioglu U., Erdogan M.F., Corapcioglu D., Kamel N. Thyrotoxic hypokalemic periodic paralysis as the first manifestation of interferoninduced Graves disease. Journal of Clinical Gastroenterology Turhan S., Tulunay C., Cin M.O., Gursoy A., Kilickap M., Dincer I., Candemir B., Gullu S., Erol C. Effects of thyroxine therapy on right ventricular systolic and diastolic function in patients with subclinical hypothyroidism: A study by pulsed wave tissue doppler imaging. Journal of Clinical Endocrinology and Metabolism Ertugrul D.T., Demirag N.G., Gursoy A., Yucel M., Sahin M., Unal A.D., Pamuk B., Berberoglu Z., Ayturk S., Tutuncu N.B. Effects of raloxifene on platelet functions in patients with postmenopausal osteoporosis. Platelets Gursoy A., Dogruk Unal A., Ayturk S., Karakus S., Nur Izol A., Bascil Tutuncu N., Guvener Demirag N. Polycythemia as the first manifestation of Cushing's disease. Journal of Endocrinological Investigation 2006.

8 53- Erdogan M.F., Gursoy A. Multiple endocrine neoplasia type 2 and sporadic medullary thyroid carcinoma: Turkish experience. Pediatric Endocrinology Reviews Gursoy A., Erdogan M.F. Severe pulmonary involvement and pheochromocytoma in atypical patient with neurofibromatosis type 1. Endocrine Practice Gursoy A., Ozduman Cin M., Kamel N., Gullu S. Which thyroid-stimulating hormone level should be sought in hypothyroid patients under L-thyroxine replacement therapy? International Journal of Clinical Practice Ozcelik T., Gullu S., Uz E., Akyerli C.B., Bagislar S., Mustafa C.A., Gursoy A., Akarsu N., Toruner G., Kamel N. Evidence from autoimmune thyroiditis of skewed X-chromosome inactivation in female predisposition to autoimmunity. European Journal of Human Genetics Tanaci N., Ertugrul D.T., Sahin M., Yucel M., Olcay I., Demirag N.G., Gursoy A. Postprandial lipemia as a risk factor for cardiovascular disease in patients with hypothyroidism. Endocrine New-onset acute heart failure after intravenous glucocorticoid pulse therapy in a patient with Graves' ophthalmopathy. Gursoy A., Cesur M., Erdogan M.F., Corapcioglu D., Kamel N. Endocrine Cesur M., Corapcioglu D., Bulut S., Gursoy A., Yilmaz A.E., Erdogan N., Kamel N. Comparison of palpation-guided fine-needle aspiration biopsy to ultrasoundguided fine-needle aspiration biopsy in the evaluation of thyroid nodules. Thyroid Erdogan M.F., Gulec B., Gursoy A., Pekcan M., Azal O., Gunhan O., Bayer A. Multiple endocrine neoplasia 2B presenting with Pseudo-Hirschsprung's disease. Journal of the National Medical Association Gursoy A., Sahin M., Ertugrul D.T., Berberoglu Z., Sezgin A., Tutuncu N.B., Demirag N.G.Familial dilated cardiomyopathy hypergonadotrophic hypogonadism associated with thyroid hemiagenesis. American Journal of Medical Genetics Gursoy A., Erdogan M.F., Kamel N. Severe reversible dilated cardiomyopathy in a patient with multiple endocrine neoplasia 2A syndrome. Journal of Endocrinological Investigation 2006.

9 63- Kamel N., Gursoy A., Koseoglulari O., Dincer I., Gullu S.Isolated office hypertension: Association with target organ damage and cardiovascular risk indices. Journal of the National Medical Association Faik Erdogan M., Gursoy A., Erdogan G., Kamel N. Radioactive iodine treatment in medullary thyroid carcinoma. Nuclear Medicine Communications Gursoy A., Kulaksizoglu M., Sahin M., Ertugrul D.T., Ozer F., Tutuncu N.B., Demirag N.G. Severe hypertriglyceridemia-induced pancreatitis during pregnancy. Journal of the National Medical Association Yaman O., Akand M., Gursoy A., Erdogan M.F., Anafarta K.The effect of diabetes mellitus treatment and good glycemic control on the erectile function in men with diabetes mellitus-induced Erectile dysfunction: A pilot study. Journal of Sexual Medicine Erdogan M.F., Gursoy A, Kadioglu P., Bald M.K., Yetkin I., Kabalak T., Erdogan G.,., Ozgen G., Cakir M., Bayram F., Ersoy R., Algun E., Cetinarslan B., Comlekci A. Ret proto-oncogene mutations in apparently sporadic Turkish medullary thyroid carcinoma patients: Turkmen study. Journal of Endocrinological Investigation Gullu S., Gursoy A., Erdogan M.F., Dizbaysak S., Erdogan G., Kamel N. Multiple endocrine neoplasia type 2A/localized cutaneous lichen amyloidosis associated with malignant pheochromocytoma and ganglioneuroma. Journal of Endocrinological Investigation Duzgun N., Morris Y., Gullu S., Gursoy A., Ensari A., Kumbasar O.O., Duman M. Diabetes insipidus presentation before renal and pulmonary features in a patient with Wegener's granulomatosis. rheumatology International Gursoy A., Erdogan M.F., Cin M.O., Cesur M., Baskal N. Effect of sibutramine on blood pressure in patients with obesity and well-controlled hypertension or normotension. Endocrine Practice Gursoy A., Cesur M., Aktas B., Utkan G., Gedik V.T., Erdogan M.F., Kamel N.Intracranial aggressive fibromatosis presenting as panhypopituitarism and diabetes insipidus. Pituitary Kamel N., Corapcioglu D., Sahin M., Gursoy A., Kucuk O., Aras G. I-131 therapy for thyroglobulin positive patients without anatomical evidence of persistent disease. Journal of Endocrinological Investigation 2004.

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