5 th ISTANBUL SYMPOSIUM: BIOENGINEERING APPROACHES ON ON PEDIATRIC CARDIOVASCULAR MEDICINE. Koç University, Engineering Auditorium 19 April 2013



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5 th ISTANBUL SYMPOSIUM: BIOENGINEERING APPROACHES ON ON PEDIATRIC CARDIOVASCULAR MEDICINE Koç University, Engineering Auditorium 19 April 2013 Scientific Co-Chairs: Kerem Pekkan, PhD & Akif Ündar, PhD Contact: snargul@ku.edu.tr Registration is free of charge. Please contact snargul@ku.edu.tr 2013 2012 ABC s of Pediatric Cardiovascular Research Applications of Computational Fluid Dynamics Importance of Multidisciplinary Team Approach Methods & Techniques for Improved Outcomes 1

Invitation to Attend The 5th Istanbul Symposium is intended for medical, engineering and nursing students, scientists, pediatric heart surgeons, engineers, cardiologists, intensivists, neonatologists, anesthesiologists, neurologists, pediatric perfusionists, respiratory therapists, nurses, residents and fellows. All are invited and encouraged to attend. Invited Faculty Mehmet A. Ağırbaşlı, MD Dept. of Cardiology, Marmara Atıf Akçevin, MD Dept. of Cardiovascular Surgery, Medipol University, Tijen Alkan-Bozkaya, MD Dept. of Cardiovascular Surgery, Medipol University, Ebru Aygar, RN American Hospital, Intensive Care Unit, Ihsan Bakır, MD Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Hakan Ceyran, MD Istanbul Koşuyolu Heart Hospital, Cardiovascular Surgery, Sertaç Haydın, MD Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Ender Ödemiş, MD Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Ebru Toksoy Oner, PhD Dept. of Bioengineeering, Marmara University, Istanbul, Kerem Pekkan, PhD Dept. Of Mechanical Engineering, Koc University, Istanbul, Şevket Ruacan, MD, Dean, College of Medicine, Koç Ayda Türköz, MD Başkent University, Department of Anethesiology, Istanbul, Rıza Türköz, MD Başkent University, Department of Cardiovascular Surgery, Akif Ündar, PhD Penn State Hershey Pediatric Cardiovascular Research Center, Penn State Hershey College of Medicine, Penn State Hershey Children s Hospital, Hershey, PA, USA Invited Students Songül Yaşar Yıldız, PhD Candidate. Dept. of Bioengineering, Marmara University, Mithat Kasap, MD PhD Candidate. Dept. of Bioengineering & Biochemistry, Marmara Ibrahim Cansaran Tanıdır Mehmet Akif Ersoy Surgery Center Department of Pediatric Cardiology, Ceren Bas School or Medicine, Koc Mehmet Berk Yiğit College of Engineering, Koc University, Istanbul 2

SCIENTIFIC PROGRAM 9:00 9:15 am Welcome Şevket Ruacan, MD, Dean & Kerem Pekkan, PhD - College of Medicine, Koç 9:15 10:00 am ABC s of Pediatric Cardiovascular Research for Medical, Engineering and Nursing Students Akif Ündar, PhD Penn State Hershey Pediatric Cardiovascular Research Center, Penn State Hershey College of Medicine, Penn State Hershey Children s Hospital, Hershey, PA, USA 10:00 10: 20 am Break 10:20 11:00 am Key Note Lecture - Applications of Computational Fluid Dynamics to solve pediatric cardiovascular problems Kerem Pekkan, PhD Dept. Of Mechanical Engineering, Koc Introduction: Akif Ündar, PhD 11:00 am Noon CASE STUDY: Novel fenestration designs for controlled venous flow shunting in failing Fontans with systemic hypertension 12:00 13:00 pm Lunch Cardiac Surgeon: Definition of the problem Rıza Türköz, MD Başkent University, Department of Cardiovascular Surgery, Scientist: Suggested Solution - Kerem Pekkan, PhD 13:00 13:30 pm What are the real problems for pediatric cardiac patients in? Why multi-disciplinary approach is necessity, not an option? Atıf Akçevin, MD Dept. of Cardiovascular Surgery, Medipol 13:30 15:00 pm PANEL: Importance of Multidisciplinary Team Approach to Improve the Outcomes During and After Neonatal and Pediatric Cardiopulmonary Bypass Procedures in Moderators: Atıf Akçevin, MD and Ihsan Bakır, MD 3

15:00 15:15pm Break Pediatric Cardiologists Perspective Ender Ödemiş, MD Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, (20 min) Pediatric Cardiac Surgeons Perspective Hakan Ceyran, MD Istanbul Koşuyolu Heart Hospital, Cardiovascular Surgery, (20 min) Pediatric Anesthesiologists Perspective Ayda Türköz, MD Başkent University, Department of Anethesiology, (20 min) Pediatric Nurses Perspective Ebru Aygar, RN Amerikan Hospital, Intensive Care Unit, Istanbul, (20 min) 15:15 16:30pm MINI-SYMPOSIUM: STUDENTS RESEARCH PROJECTS Moderators: Ebru Toksoy Oner, PhD and Mehmet A. Ağırbaşlı, MD Functionally Stable Plasminogen Activator Inhibitor-1 In A Family With Cardiovascular Disease And Vitiligo Songül Yaşar Yıldız, PhD Dept. of Bioengineeering, Marmara (15 min) Atriyal Fibrilasyonda evde görüntüleme sistemi Mithat Kasap, MD Dept. of Bioengineering & Biochemistry, Marmara (15 min) Impact of NIRS during cardiac catherization Inrahim Cansaran Tanıdır, MD Mehmet Akif Ersoy Surgery Center Department of Pediatric Cardiology, (15 min) Shear stress induced improvement in erythrocyte deformability Ceren Bas, School or Medicine, Koc (15 min) Biomechanical Modeling from Fatal to Neonatal Circulation Mehmet Berk Yiğit, College of Engineering, Koc University, Istanbul (15 min) 16:30 18:30pm PANEL: Pediatric ECLS Systems & Novel Techniques and Methods to Minimize the Injury during neonatal/pediatric Cardiopulmonary Bypass Procedures Moderators: Hakan Ceyran, MD and Rıza Türköz, MD 4

Pediatric Extracorporeal Life Support Systems in 2012 Update Sertaç Haydın, MD Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Monitoring Biomarkers After Pediatric Cardiac Surgery: A New Paradigm in the Horizon Mehmet A. Ağırbaşlı, MD Dept. Of Cardiology, Marmara IBSB: Multinational Research Activities on Glycotechnology Ebru Toksoy Öner, PhD Dept. of Bioengineeering, Marmara Impact of Pulsatile Perfusion on Clinical Outcomes of Neonates and infants with Complex Pathologies undergoing Cardiopulmonary Bypass Procedures Tijen Alkan-Bozkaya, MD Dept. of Cardiovascular Surgery, Medipol Importance of Neonatal/Pediatric oxygenators with or without Arterial Filters for capturing microemboli during CPB procedures Akif Ündar, PhD 18:30pm Closing Remarks - Kerem Pekkan, PhD 5

Graduate Student Oath I have entered the serious pursuit of new knowledge as a member of the community of graduate students at Penn State College of Medicine. I will strive to uphold the values of integrity, professionalism, and scholarship. INTEGRITY I will uphold academic and scientific honesty. I will conduct research objectively, using my knowledge responsibly. I will not allow financial gain, competition, or personal ambition to cloud my judgment in the conduct of ethical research and scholarship. PROFESSIONALISM I will share knowledge and resources resulting from my research, within the limits of intellectual property agreements. I will contribute to the public understanding of the scientific process and the impact of my results. I will minimize the adverse effects of my research on people, animals and the natural world. SCHOLARSHIP I will report my results accurately regardless of the expectations set forth by myself, the scientific community, or funding sources. I will recognize the limits of my knowledge and will pursue lifelong learning. I will fulfill my responsibility to mentor and instruct the next generation of scientists. 6