ÖZGEÇMİŞ Adı Soyadı: Özlem Dilek Ünvan: Yrd. Doç. Dr. Öğrenim Durumu: Derece Bölüm/Program Üniversite Yıl Lisans Kimya Orta Doğu Teknik Üniversitesi 1997 Y. Lisans Organik Kimya Orta Doğu Teknik Üniversitesi 2001 Doktora Kimyasal Biyoloji New York Eyalet Üniversitesi- (SUNY) Binghamton, NY USA 2009 Yüksek Lisans Tez Başlığı ve Tez Danışmanı: 1,3-dipolar cycloaddition reactions of some 3-aryl-phthalazinium-1-olates. Danışman: Prof. Dr. Lemi Türker Doktora Tez Başlığı ve Danışmanı : Synthesis and spectroscopic characterization of fluorescent boron dipyrromethenes probes for site specific bioorthogonal labeling of proteins. Danışman: Prof. Dr. Susan L. Bane Görevler: Görev Görev Yeri Yıl Ünvanı Uzman TÜBİTAK-ULAKBİM 1999-2004 Araş. Gör. New York Eyalet Universitesi-Binghamton Kimya Bölümü 2004-2007 Araş. Gör. Research Foundation of New York-Binghamton Araştırma 2007-2009 Dr. Postdoc Cornell Üniversitesi, Kimya ve Kimyasal Biyoloji Bölümü 2009 Dr. Postdoc Research Foundation of New York-Binghamton ve North 2009-2012 Carolina Üniversitesi, Chapel Hill Tıp Fakültesi Yrd.Doç. Dr. İstanbul Kemerburgaz Üniversitesi, Tıp Fakültesi, Biyokimya Anabilim dali 2013-halen Projelerde Yaptığı Görevler: National Institute of Health (NIH), Ulusal Amerikan Sağlık Örgütü Proje No: R01-CA69571-Araştırmacı 2007-2009 National Institute of Health (NIH), Ulusal Amerikan Saglik Orgutu Proje No: R15-GM09394-Postdoc Araştırmacı 2010-2012
Verdiği dersler ve danışmanlıklar 2004-2005 Öğretim Görevlisi, SUNY-Binghamton, Genel Kimya Lab 107,108 2005-2007 Öğretim Görevlisi SUNY-Binghamton, Organik Kimya 332, 335 2007-2008 Mentör, SUNY-Binghamton, Lisans Öğrenci Bağımsız Araştırma Proje ve Dönem Araştırma Dersleri 2008-2012 Mentör, SUNY-Binghamton, Yüksek Lisans ve Lisans Öğrenci Bağımsız Araştırma Proje ve Dönem Araştırma Dersleri İdari Görevler : 2005-2006 New York Eyalet Üniversitesi-Binghamton, Yüksek Lisans Öğrenci Organizasyonu, Kimya Bölümü Temsilcisi 2007-2008 New York Eyalet Üniversitesi-Binghamton, Yüksek Lisans Öğrenci Organizasyonu, Kimya Bölümü Temsilcisi 2008-2009 New York Eyalet Üniversitesi-Binghamton, Doktora Kimya Klübü Sekreter Bilimsel Kuruluşlara Üyelikler : 2004-halen 2006-halen 2007-halen 2010-halen American Chemical Society New York Academy of Sciences Biophysical Society American Society for Cell Biology Ödüller : 2004-2007 SUNY-Binghamton, Kimya Bölümü-Tam doktora bursu ve asistanlık 2007-2009 SUNY-Binghamton, Research Foundation of NY- Tam araştırma doktora bursu ve asistanlık 2007 SUNY-Binghamton, Yüksek Lisans Organizasyonu Seyahat Ödülü. 2008 American Chemical Society (ACS), Binghamton Birimi, Öğrenci Seyahat Ödülü 2009 American Chemical Society (ACS), Binghamton Birimi, Öğrenci Seyahat Ödülü 2009 American Chemical Society (ACS), Organik Kimya Birimi, Ulusal Öğrenci Seyahat Ödülü 2010 American Chemical Society (ACS), Zappert Ödülü Seçkin Doktora Öğrencisi Ödülü 2012 American Society for Cell Biology (ASCB), Doğa Bilimler Postdoc Ödülü
ESERLER A. Uluslararası hakemli dergilerde yayımlanan makaleler (SCI & SSCI & Arts and Humanities) : A1. Dilek O.; Bane SL, Tetrahedron Letters, Synthesis of fluorescent boron dipyrromethenes for bioorthogonal labeling, 2008, 49, 1413. A2. Dilek O.; Bane SL, Bioorganic Medicinal Chemistry Letters, Synthesis and spectroscopic properties and protein labeling of water soluble 3,5-disubstituted boron dipyrromethenes. 2009, 19, 6911. A3. Dilek O.; Bane SL, Journal of Fluorescence, Syntheses and spectroscopic characterization of boron dipyrromethene-derived hydrazones. 2011, 21, 1, 347. A4. Shanker N.; Dilek O.; Mukherjee K.; McGee WD.; Bane SL, Journal of Fluorescence, Aurones: Small Molecule Visible Range Fluorescent Probes for Biomacromolecules. 2011, 21, 6, 2173. A5. Blanden A.R., Mukherjee K., Dilek O., Loew M., Bane S.L., Bioconjugate Chemistry, 4-Aminophenylalanine as a biocompatible nucleophilic catalyst for hydrazone-ligations at low temperature and neutral ph. 2011, 22, 10, 1954 B. Uluslararası bilimsel toplantılarda sunulan ve bildiri kitabında (Proceedings) basılan bildiriler : B1. A. Banerjee, T. D. Panosian, B. Cowen, O. Dilek, N. Shanker, R. Ravindra, D. L. Sackett, S. Bane, Versatile Yet Highly Specific Fluorescent Labeling of Tubulin. presented at 46th Annual American Society for Cell Biology, 9-13 December 2006, San Diego, CA, USA B2. Susan L. Bane, Abhijit Banerjee, Ozlem Dilek, Strategies for Site-Specific Labeling of Proteins with Fluorescent Small Molecules. presented at American Chemical Society, 35th Northeast Regional Meeting (NERM), October 5 7 2006, Binghamton, NY USA B3. Dilek O., Bane S., Synthesis of BODIPY-based Hydrazine Derivatives as Fluorescent Probes presented at American Chemical Society, 35th Northeast Regional Meeting (NERM), October 5 7 2006, Binghamton, NY, USA. B4. Dilek O, Bane S., Boron dipyrromethene fluorescent probes for bioorthogonal labeling presented at the 233rd National American Chemical Society, 24-29 March 2007, Chicago, USA. B5. Dilek O, Bane S., Boron dipyrromethene fluorescent probes for bioorthogonal labeling presented at the 2nd Annual Binghamton Biomedical Research Conference, 5 May 2007, Binghamton, NY, USA
B6. Dilek O, Bane S., Synthesis and biological applications of water soluble 3,5- disubstituted boron dipyrromethenes presented at the 3rd Annual Binghamton Biomedical Research Conference, 3 May 2008, Binghamton, NY, USA. B7. Dilek O, Banerjee A. Bane S., Chemoenzymatic method for site specific fluorescent labeling of tubulin presented at the 9th Tetrahedron Symposium, 22-25 July 2008, Berkeley, CA, USA. B8. Dilek O, Bane S., Syntheses and spectral characterization of water soluble 3,5- disubstituted boron dipyrromethenes for biolabeling presented at the 236rd National American Chemical Society, 17-21 August 2008, Philadelphia, USA. B9. Dilek O, Bane S. Synthesis and spectroscopic studies on hydrazine/hydrazon turn-on fluorescent probe systems for site specific bioorthogonal labeling of proteins presented at the 238rd National American Chemical Society, 16-20 August 2009, Washington, D.C. USA B10. Blanden A.R., Dilek O., Mukherjee K., Loew M., Kuperman R., Bane S.L. Nucleophilic catalysis expands repertoire for hydrazine-based bioorthogon - tubulin C-terminus presented at the 240 th National American Chemical Society, 22-26 August 2010, Boston, MA. USA B11. Mukherjee K., Kong S.L., Dilek O., Yoffe G. P., Bane S.L. High-throughput screening assay for modulators of tubulin tyrosine ligase at the 57 th Annual Biophysical Society, 2-6 Şubat 2013, Philadelphia, PA USA B12. Dilek O., Mukherjee K., Bane S.L. Fluorescent Probes for Carbonyl-Containing Proteins at the Annual American Society for Cell Biology, 15-19 Aralık 2012, San Francisco, LA USA C. Yazılan uluslararası kitaplar veya kitaplarda bölümler: C1. Dilek O.; Bane SL. Aromatic Hydrazine-Based Fluorophores: Synthesis, Spectroscopy and Bioapplications. Nova Science Publishers, NY USA (2013) yayında. D. Davetli seminerler: D1. Boron dipyrromethene fluorescent derivatives for bioorthogonal labeling of biomolecules. New York University, School of Medicine, January 2009 New York, NY USA D2. Synthesis and characterization of boron dipyrromethene derivatives bioorthogonal labeling of proteins Cornell University, Chemistry and Chemical Biology Department, January 2009 Ithaca, NY USA D3. Synthesis and characterization of fluorescent boron dipyrromethene (BDP) probes for site specific bioorthogonal labeling of proteins Cornell University, Weill Medical School, December 17 2009 New York, NY USA
D4. Boron dipyrromethene fluorophores for bioorthogonal site-specific labeling of proteins University of North Carolina- Chapel Hill, School of Medicine, April 12 2010, Chapel Hill, NC USA. D5. Synthesis of hydrazine-based bioorthogonal fluorophores: A logical approach to turn-on targeting. METU, Biotechnology Department, September 14 2011, Ankara, Turkey. D6. Bioorthogonal fluorophores for turn-on targeting of proteins Bilkent University- UNAM, January 24 2011, Ankara, Turkey. D7. Design of hydrazine based fluorophores for site-specific turn on targeting of proteins. Ankara University, Chemistry Department, December 25 2012, Ankara, Turkey. D8. Fluorescent probes for site-specific turn on targeting of proteins. Bogazici University, Molecular Biology and Genetics Department, February 1 2013, Istanbul, Turkey. E. Diğer yayınlar ve aktiviteler: E1. Dilek O, Bane S., Boron dipyrromethene fluorescent probes for bioorthogonal labeling presented at the 3rd Annual Binghamton Biological Symposium, 25 January 2008, Binghamton, NY, USA. E2. Professor Kevin Burgess (Texas A&M University) Fluorescent Probes for Multiplexed Intracellular Imaging SUNY-Binghamton, NY January 2009. Seminer Organizasyon Sorumlusu E3. Fundamentals and Applications of Fluorescence Spectroscopy in Modern Cell Biology Kursu, Koç Üniversitesi, Tıp Fakültesi, İstanbul 12-17 August 2012