CURRICULUM VITAE. Personal Details. Surname: Kaygusuz. First Name: Irfan. Academic title/position: Associate Professor, M.D

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1 CURRICULUM VITAE Personal Details Surname: Kaygusuz First Name: Irfan Academic title/position: Associate Professor, M.D Key Qualifications: Otolaryngology Head and Neck Surgery Research Interest: Rhinology International Experience/Collaborations: Contact Details Work Address: Name of Hospital: Firat University Hospital Street Town: Elazig Country: Turkey Post Code: Phone/Fax: / Date of Birth: Place and Country of Birth: Elazig/Turkey Country of Citizenship: Turkish Republic members Country of Training: Turkey First Language: Turkish Languages: English

2 Academic Details Faculty/University (name and address): Istanbul Medical Faculty of Istanbul University Date of Graduation: Postgraduate Training: (Name and address of Center and Supervisor[s] in charge of Training): Medical Faculty of Firat University Professor Şinasi yalçın Professor Onur Çelik Professor Üzeyir Gök SUPERVISOR IN CHARGE OF TRAINING: Professor Onur Çelik From 1994 To 1998 Title of thesis: Effects of Interferon- -2b and octreotide on healing of esophageal corrosive burns Accreditation: (Name, number and date of certificate issued by University, Medical Association or Government Body) Academic Experience: Member of the Medical Faculty Administrative Committee October Society member of Healthy Sciences October March 2007 Director of Otorhinolaryngology October March 2007 Assistant Dean of Medical Faculty September October 2008 Director of Firat University Hospital August August 2008 Memberships: Turkish Otorhinolaryngology Head and Neck Surgery Society Firat- Dicle Otorhinolaryngology Head and Neck Surgery Society Turkish Rhinologic Society International Rhinologic Society

3 International Publications: 1. Kaygusuz, I., A. Oztürk, B. Ustundag, S. Yalcin, Role of free oxygen radicals in noise-related hearing impairment, Hear. Res, 162, (2001). 2. Kaygusuz, I., U. Gok, S. Yalcin, E. Keles, A. Kizirgil, E. Demirbag, Bacteremia during tonsillectomy, Int. J. Pediatr. Otorhinolaryngol, 58, (2001). 3. Kaygusuz, I., O. Celik, O. Ozkaya, S. Yalcin, E. Keles, T. Cetinkaya, Effects of interferon-alpha-2b and octreotide on healing of esophageal corrosive burns, Laryngoscope, 111, (2001). 4. Kaygusuz, I., S. Yalcin, E. Keles, Leechs in the larynx, Eur. Arch. Otorhinolaryngol, 258, (2001). 5. Kamanli, A., U. Gok, S. Sahin, I. Kaygusuz, O. Ardicoglu, S. Yalcin, Bilateral cricoarytenoid joint involvament in a patient with rheumatoid arthritis: a case report, Rheumatology, 40, (2001). 6. Karlidag, T., K. Demirdag, I. Kaygusuz, M. Ozden, S. Yalcin, L. Ozturk, Resistant bacteria in the adenoid tissues of children with otitis media with effusion, Int. J. Pediatr. Otorhinolaryngol, 64, (2002). 7. Karlidag, T., S. Yalcin, A. Ozturk, B. Ustundag, U. Gok, I. Kaygusuz, N. Susaman, The role of free oxygen radicals in noise induced hearing loss: effects of melatonin and methylprednisolone, Auris. Nasus. Larynx, 29, (2002). 8. Karlidag, T., S. Yalcin, I. Kaygusuz, E. Demirbag, Bilateral pneumosinus dilatans of the maxillary sinuses", Brit. J. Oral. Maxillofac. Surg, 41, (2003). 9. Kaygusuz, I., A. Kizirgil, T. Karlidag, S. Yalcin, E. Keles, Y. Yakupogullari, H.C. Alpay, Bacteremia in septoplasty and septorhinoplasty surgery, Rhinology, 41, (2003). 10. Aral, M., E. Keles, I. Kaygusuz, The microbiology of ethmoid and maxillary sinuses in patients with chronic sinusitis, Am. J. Otolaryngol, 24, (2003). 11. Kaygusuz, I., N. Susaman, The effects of dexamethasone, bupivacaine and topical lidocaine spray on pain after tonsillectomy, Int. J. Pediatr. Otorhinolaryngol, 67, (2003). 12. Yalcin, S., T. Karlidag, I. Kaygusuz, E. Demirbag, First branchial cleft sinus presenting with cholesteatoma and external auditory canal atresia, Int. J. Pediatr. Otorhinolaryngol, 67, (2003). 13. Kaygusuz, I., N. Ilhan, T. Karlidag, E. Keles, S. Yalcin, H. Cetiner, Free radicals and scavenging enzyme in chronic tonsillitis, Otolaryngol. Head. Neck. Surg, 129, (2003). 14. Kaygusuz, I., A. Godekmerdan, T. Karlidag, E. Keles, S. Yalcin, I. Aral, M. Yildiz, Early stage impacts of tonsillectomy on immune functions of children, Int. J. Pediatr. Otorhinolaryngol, 67, (2003). 15. Karlidag, T., N. Ilhan, I. Kaygusuz, E. Keles, S. Yalcin, The role of antioxidant and free oxygen radicals on typanosclerosis development, Laryngoscope, 114, (2004). 16. Kaygusuz, I., T.O. Kaygusuz, A. Ozturk, S.S. Kilic, T. Karlidag, E. Keles, S. Yalcin, Effects of interferon-α2b on hearing, Int. J. Audiology, 43, (2004).

4 17. Kaygusuz, I., A. Godekmerdan, E. Keles, T. Karlidag, S. Yalcin, M. Yildiz, A. Tazegul, The role of viruses in idiopathic peripheral facial palsy and cellular immune respond, Am. J. Otolaryngol,25, (2004). 18. Ozturk. A., S. Yalcin, I. Kaygusuz, S. Sahin, U. Gok, T. Karlidag, O. Ardicoglu, High frequency hearing loss and middle ear involvement in Rheumatoid Arthritis, Am. J. Otolaryngol, 25, (2004). 19. Keles. E., I. Kaygusuz, T. Karlidag, S. Yalcin, Y. Acik, H.C. Alpay, O. Sakallioglu, Prevalence of omits media with effusion in first and second grade primary school students and its correlation with BCG vaccination, Int. J. Pediatr. Otorhinolaryngol, 68, (2004). 20. Karlidag. T., I. Kaygusuz, E. Keles, S. Yalçın, S.S. Serhatlioglu, Y. Acik, L. Ozturk, Hearing in workers exposed to low-dose radiation for a long period, Hear. Res, 194, (2004). 21. Keles, E., A. Godekmerdan, T. Karlidag, I. Kaygusuz, S. Yalcin, H.C. Alpay, M. Aral, Meniere s disease and allergy: allergens and cytokines, J. Laryngol. Otol, 118, (2004). 22. Karlidag, T., N. Ilhan, I. Kaygusuz, E. Keles, S. Yalcin, M. Yildiz, Roles of free radicals nitric oxide, and scavenging enzymes in nasal polyp development, Ann. Otol. Rhinol. Laryngol, 114, (2005). 23. Kaygusuz, O.T., I. Kaygusuz, S.S. Kilic, S. Yalcin, S. Felek, Investigation of the hearing loss in patients with acute brucellosis by using standart and high frequencies audiometry, Clinical Microbiology and Infection, 11, (2005). 24. Karlidag, T., Y. Bulut, E. Keles, I. Kaygusuz, S. Yalcin, A. Ozdarendeli, H. Dabak, Detection of helicobacter pylori in the children with otitis media with effusion: A preliminary report, Laryngoscope, 111, (2005). 25. Keles, E., Y. Bulut, I. Kaygusuz, T. Karlidag, S. Yalcin, A. Ozdarendeli, H.C. Alpay, Identification of Chlamidia trachomatis with polymerase chain reaction in middle ear fluid in otitis media with effusion, Indian Pediatr,42, (2005). 26. Keles, E., A. Kizirgil, I. Kaygusuz, T. Karlidag, S. Yalcin, H.C. Alpay, Y.S. Demir, Bacteremia during mastoidectomy and/or tympanoplasty, Otolaryngol Head Neck Surg, 133, (2005). 27. Kaygusuz, I., Letter to the editor, Int. J. Pediatr. Otorhinolaryngol, 70, 177 (2006). 28. Keles, E., A. Godekmerdan, T. Karlidag, I. Kaygusuz, S. Yalcin, H.C. Alpay, A. Tazegul, Otitis media with effusion and BCG vaccine. Cytokines and immunglobilins, Meditter J. Otol, 2, (2006). 29. Godekmerdan, A., I. Kaygusuz, O. Sakallıoglu, F. Ilhan, N. Demir, Evaluation of The cellular immune response in patients with head and neck cancer, Journal Clinical Diagnostic Research, 1, (2007). 30. Karlidag, T., B. Cobanoglu, E. Keles, H.C. Alpay, I. Ozercan, I. Kaygusuz, S. Yalcin, O. Sakallioglu, Expression of bax, p53, and p27/kip in patients with papillary thyroid carcinoma with or without cervical nodal metastasis, Am J Otolaryngol, 28, (2007). 31. Alpay, H.C., T. Karlidag, E. Keles, I. Kaygusuz, S. Yalcin, Z. Kapusuz. The effects of fine-needle biopsy on thyroid hormone levels. Otolaryngol Head Neck Surg, 136, (2007) 32. Alpay, H.C., I. Kaygusuz, T. Karlidag, I. Orhan. Thermal burn of the larynx in an adult following hot water aspiration, Otolaryngol Head Neck Surg, 139, (2008).

5 33. Ozturk, L., I. Kaygusuz, N. Akpolat, E. Keles, T. Karlidag, H.C. Alpay, S. Yalcin. Histopathologic changes in guinea pig mastoid mucosa after topical mitomycin C application followed by mastoidectomy, Am J Otolaryngol, 29, (2008). 34. Kaygusuz, I., H.C. Alpay, A. Godekmerdan, T. Karlidag, E. Keles, S. Yalcin, N. Demir. Evaluation of long-term impacts of tonsillectomy on immune functions of children: A follow up study, Int. J. Pediatr. Otorhinolaryngol, (Accepted). Presentations at International Scientific Meetings 1. Gok, U., O. Celik, S. Yalcin, I. Kaygusuz, T. Karlidag, Ototransfusion ın the carcinoma of larynx, First International Voice Symposium, p. 1, Ankara, Turkey, Celik,O., U. Gok, S. Yalcin, N. Susaman, I. Kaygusuz, T. Karlidag, Results of ossiculoplasty ın chronic otitis media without cholesteatoma, Politzer Society, p.39, Antalya, Turkey, Kaygusuz, I., T. Karlidag, U. Gok, N. Susaman, E. Demirbag, S. Yalcin, Fonksiyonel endoskopik sinüs cerrahisi sonuçlarımız International Otorhinolaryngology-Head and Neck Surgery Meeting, p. 136, Ankara, Turkey, Kaygusuz, I., T. Karlidag, U. Gok, N. Susaman, E. Demirbag, S. Yalcin, Paranazal sinüs enfeksiyonlarında anatomik varyasyonların ve bilgisayarlı tomografinin önemi, International Otorhinolaryngology-Head and Neck Surgery Meeting, p. 132, Ankara, Turkey Susaman N., S. Yalcin, I. Kaygusuz, U. Gok, H. I. Ozercan, T. Karlidag, Travmatik timpanik membran perforasyonlarında histopatolojik değişiklikler üzerine E vitamininin etkisi, International Otorhinolaryngology-Head and Neck Surgery Meeting, p. 115, Ankara, Turkey, Karlidag T., S. Yalcin, U. Gok, I. Kaygusuz, B. Ustundag, N. Susaman, Gürültünün oluşturduğu koklear hasarda serbest oksijen radikallerinin rolü:meletonin ve metilprednizolonun etkinliği, International Otorhinolaryngology-Head and Neck Surgery Meeting, p. 108, Ankara, Turkey, Keles E., A. Kizirgil, I. Kaygusuz, T. Karlidag, S. Yalcin, H.C. Alpay, Y.S. Demir, Timpanoplasti esnasında bakteriyemi, Kulak Burun Boğaz ve Baş Boyun Cerrahisi 6. Uluslar arası Toplantıs ı-kbb de Minimal Đnvaziv Yaklaşımlar-, p , Ankara, Türkiye, Keles E., Y. Bulut, I. Kaygusuz, T. Karlidag, S. Yalcin, A. Ozdarendeli, H.C. Alpay, Efüzyonlu otitis media da orta kulak sıvısında polimeraz zincir reaksiyonu ile Chlamydia Spp, Kulak Burun Boğaz ve Baş Boyun Cerrahisi 6. Uluslar arası Toplantısı -KBB de Minimal Đnvaziv Yaklaşımlar-, p , Ankara, Türkiye, Oztürk L., I. Kaygusuz, N. Akpolat, T. Karlidag, E. Keles, S. Yalcin, Topikal Mitomisin C nin mastoidektomi sonrası guinea pig mastoid mukozasında oluşturduğu histopatolojik değişiklikler: Deneysel hayvan modeli, Kulak Burun Boğaz ve Baş Boyun Cerrahisi 6. Uluslar arası Toplantısı -KBB de Minimal Đnvaziv Yaklaşımlar-, p , Ankara, Türkiye, Karlidag T., I. Kaygusuz, E. Keles, S. Yalcin, S. Serhatlioglu, Y. Acik, L. Ozturk, Uzun süre düşük doz radyasyona maruz kalanlarda işitme bulguları, Kulak Burun Boğaz ve Baş Boyun Cerrahisi 6. Uluslar arası Toplantısı -KBB de Minimal Đnvaziv Yaklaşımlar-, p , Ankara, Türkiye, 2003.

6 11. Godekmerdan A., I. Kaygusuz, O. Sakallioglu, F. Ilhan, N. Demir. Evaluation of cellular immune response in patients with head and neck cancer, 1 st Joint meeting of European National Societies of Immunology- 16 th European Congress of Immunology, p.393, Paris, France, 2006.