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Personal Information Email: Web: https://avesis.ege.edu.tr/gulten.kantarci gulten.kantarci@ege.edu.tr Education Information Prof. AYŞE GÜLTEN KANTARCI Doctorate, Under Graduate, Ege Üniversitesi, Ege Üniversitesi, Sağlık Eczacılık Bilimleri Fakültesi, Enstitüsü, Eczacılık Farmasötik Pr., Mikrobiyoloji Turkey 1974 -(Yl), 1978 Turkey 1980-1987 Research Areas Academic Titles / Tasks Professional Experience Health Sciences, Pharmacology and Therapeutics, Pharmaceutics Technology, Pharmaceutical Biotechnology Professor, Ege Üniversitesi, Eczacılık Fakültesi, Eczacılık Teknolojisi Bölümü, 2013 - Continues Head of Department, Ege Üniversitesi, Eczacılık Teknolojisi, Eczacılık Teknolojisi, 2018 2015 - Continues 2018 Advising Theses KANTARCI etkinliklerinin A. G. değerlendirilmesi, Glioblastoma Multiforme Doctorate, tedavisinde G.EREL(Student), kullanılmak 2018üzere sirna taşıyıcı sistemlerin geliştirilmesi ve KANTARCI manyetofeksiyon, A. G. Yeni Doctorate, bir manyetik H.AKBABA(Student), nanopartikül üretim 2016 yöntemi ve manyetik alan düzenlemeleri altında KANTARCI Post Graduate, A. G. G.EREL(Student), Oral uygulama amacıyla 2015 insülin taşıyıcı sistemlerin hazırlanması, karakterizasyonu ve salım çalışmaları, KANTARCI 2014 A. G. Dermal uygulama amacıyla DNA taşıyıcı sistemlerin hazırlanması, Post Graduate, U.KARAGÖZ(Student), KANTARCI Doctorate, M.KOTMAKÇI(Student), A. G. İlaç direncine karşı 2013 shrna kodlayan dna taşıyıcı sistemlerin formülasyonu ve in vitro değerlendirilmesi, KANTARCI Graduate, T.YILMAZ(Student), A. G. DNA taşıyıcı sistem 2012 geliştirme amacıyla manyetik nanopartikül formülasyonların hazırlanması, Post KANTARCI Graduate, H.AKBABA(Student), A. G. Gen tedavisi amacıyla 2010 DNA yüklü katı lipid nanopartikül formülasyonlarının hazırlanması, Post KANTARCI A. G., Vücut organlarına hedefleme amacıyla hazırlanan Mitomisin-C yüklü taşıyıcı sistemlerin organizmada biyodağılımının incelenmesi, Post Graduate, M.KOTMAKCHİEV(Student), 2009 Articles Published in Journals That Entered SCI, SSCI and AHCI Indexes

Articles Published in Journals That Entered SCI, SSCI and AHCI Indexes A preparation, promising approach characterization, to develop cytotoxicity nanostructured and nucleic lipid acid carriers binding from ability solid lipid nanoparticles: Oner PHARMACEUTICAL E., KOTMAKÇI M., DEVELOPMENT KANTARCI A. AND G. Comparison of different w o microemulsions TECHNOLOGY, contain 2020 diclofenac (Journal Indexed sodium in preparation SCI) release rate and skin irritation studies characterization KANTARCI AAPSPharmSciTech, A. G., ÖZGÜNEY vol.8, 2007 I., KARASULU (Journal Indexed H. Y., ARZIK in SCI S., Expanded) GÜNERİ T. Transdermal ÖZGÜNEY I., KARASULU Delivery H. of Y. Diclofenac, KANTARCI Sodium A. G., SÖZER Through KARADAĞLI Rat Skin L. S. from, GÜNERİ Various T., ERTAN Formulations AAPSPharmSciTech, vol.7, 2006 (Journal Indexed in SCI Expanded) G. In Skin Vitro Permeation of Diclofenac Sodium from Novel Microemulsion Formulations Through Rabbit KANTARCI Drug Development A. G., ÖZGÜNEY Research, I., KARASULU vol.65, pp.1-9, H. Y. 2005, GÜNERİ (Journal T., BAŞDEMİR Indexed in SCI G. Preparation Expanded) carcinoma cell of line arsenic trioxide-loaded microemulsion and its enhanced cytotoxicity on MCF-7 breast KARASULU DRUG DELIVERY, H. Y., KARABULUT vol.11, pp.345-350, B., KANTARCI 2004 (Journal A. G., ÖZGÜNEY Indexed in I., SCI) SEZGİN C., ŞANLI U. A., GÖKER E. Articles Published in Other Journals Preparation, gene delivery characterization to MCF-7 cells and evaluation of solid lipid nanoparticles and niosomes for ING4 Karagoz JOURNAL U., OF KANTARCI RESEARCH A. IN G. MUTASYON DNA HASARI PHARMACY, ONARIM MEKANİZMALARI vol.23, pp.935-943, VE 2019 KANSERLE (Journal Indexed İLİŞKİSİ in ESCI) DEBELEÇ Ankara Ecz. BÜTÜNER Fak. Derg., B., vol.35, KANTARCI pp.149-170, A. G. İzmir Yöresindeki Yabani Lavandula stoechas 2006 (Other L subsp Refereed National Journals) Yağın Bileşimi Antibakteriyal Antifungal ve Antioksidan stoechas Kapasitesi Taksonundan Elde Edilen Uçucu ÖZTÜRK Anadolu B., Ege KONYALIOĞLU Tarımsal Araştırma S., KANTARCI Enstitü Dergisi, A. G., ÇETİNKOL vol.15, pp.61-72, D. Phase Behaviour of Microemulsion Systems Containing Short 2005 Chain (Other Alcohols Refereed as National Cosurfactants Journals) KANTARCI Acta Pharmaceutica A. G., KARASULU Turcica, pp.77-85, H. Y., ÖZGÜNEY 2002 (Refereed I., GÜNERİ Journals T. In of Other Institutions) Ertan vitro G., Özgüney Dissolution I., Karasulu Studies H. on Y., Sustained Aşıkoğlu M., Release Kantarcı Dosage A. G. Forms of Ampisilin and Amoxycillin Kalsiyum ACTA PHARMACEUTICA Hidroksit Preparatlarının TURCUA, vol.36, Antibakteriyal pp.128-135, 1994 Etkileri. (Other Refereed National Journals) Gökay Ege Diş N., Hekimliği ÇALIŞKAN Fakültesi M. K., KANTARCI Dergisi, vol.13, A. G. pp.56-60,, ELTEM R. 1992 (National Refreed University Journal) Books & Book Chapters Aşılar ŞENEL BİLGE DAĞALAP S., BOZKIR s., A., GÜRHAN ÖNER A. S. F. İ., KARAAĞAOĞLU, et al. A. E., KANTARCI A. G., VURAL İ., ALPAR C. R., GÜRSOY R. N., in: Türk Farmakopesi 2017,, Editor, T.C. Sağlık Bakanlığı, Türkiye İlaç ve Tıbbi Cihaz Kurumu, Artı 6 Matbaa Ltd. Sti.,

Non-viral 2018 KANTARCI A. systems G., Cavalli for R. gene delivery; Up to date, Nanotechnology in Progress in: Kerala, Nanotechnology pp.177-208, in 2012 progress:pharmaceutical pplications, Şenyiğit T, Özcan i., Özer Ö., Editor, Research Signpost, Multiple Özer Ö., KANTARCI Emulsions A. G. in Biomedical and Biotechnological Applications in: Colloids in Biotechnology, Fanun M., Editor, Crc Press, Taylor And Francis, Usa, -, pp.331-343, 2010 Refereed Congress / Symposium Publications in Proceedings Evaluation ÖNER E., KOTMAKÇI of the effect M., DEBELEÇ of solid BÜTÜNER and cationic B., KANTARCI lipids on A. G. sirna delivery systems Development Uluslararası Bio Türkiye kkongresi 2020, 5-07 March 2020 DEBELEÇ BÜTÜNER of SIRT1 B., ÖNER sirna-carrying E., KOTMAKÇI liposomes M., KANTARCI for A. treatment G. of prostate cancer Evaluation Uluslararası Bio Türkiye Kongresi 2020, 5-07 March 2020 viraldelivery of systems the cationic solid lipid nanoparticlescarrying sirna against EphA2 receptor as non- ÖNER ESGCT E., 27th KOTMAKÇI Annual CongressIn M., Gray S., collaboration Baird A., DEBELEÇ with SETGyC, BÜTÜNER 22 B., - 25 KANTARCI October 2019, A. G., Finn vol.30, S. Solid pp.200-201 KOTMAKÇI Lipid M., Nanoparticle DÜZGÜN Z., BOZOK complexes ÇETİNTAŞ with V., plasmid KANTARCI or oligonucleotide A. G. for mir-34a delivery Solid Uluslararası IVEK-BIO Kongresi, İstanbul, Turkey, 26 November 2018, pp.1 KOTMAKÇI Lipid M., Nanoparticle DÜZGÜN Z., BOZOK (SLN) ÇETİNTAŞ Complexes V., Karagoz with Plasmid U., KANTARCI or Oligonucleotide A. G. for mir-34a Delivery Nanoparticle Uluslararası İVEK-BİO kongresi, 26-28 November 2018 KANTARCI A. G. systems for the delivery of recombinant proteins and nucleic acids Radiation-Induced Uluslarası İVEK BİO Kongresi 2018, 26-28 November 2018 EREL AKBABA G., AKBABA Targeted H., KANTARCI Nanoparticle A. G., TANNOUS BasedGene B. A. Delivery For Brain Tumors Ege 23rd Annual Metting of Neuro-Oncology, United States Of America, 15-18 November 2018 Uyumunu Üniversitesi Geliştirme, Eczacılık Öğretim Fakültesi ve Değerlendirme Lisans Eğitimi Süreçlerini Programı nın İyileştirme EczÇEP le Projesi ve Ulusal Standartlarla ALPTÜZÜN N., DURAK H. V., İ. AŞIKOĞLU, ELGİN CEBE M., BALOĞLU G., ERAÇ B., E., et BAŞPINAR al. Y., BOZKURT B., ÇETİN UYANIKGİL E. Ö., DEMİRAL YILMAZ Ege. II. Ulusal Eczacılık Eğitimi ve Akreditasyon Kongresi, Eskişehir, Turkey, 10 May 2018, pp.13 Yapılan Üniversitesi Eczacılık Eczacılık Mesleği Görev Fakültesi Analizi Eğitim Çalışması Programı İyileştirme ve Geliştirme Projesi Kapsamında ALPTÜZÜN N., DURAK H. V., İ. AŞIKOĞLU, ELGİN CEBE M., BALOĞLU G., ERAÇ B., E., et BAŞPINAR al. Y., BOZKURT B., ÇETİN UYANIKGİL E. Ö., DEMİRAL YILMAZ shrna-encoding. II. Ulusal Eczacılık Eğitimi ve Akreditasyon Kongresi, Eskişehir, Turkey, 10 May 2018, pp.16 treatment of androgenic plasmid alopecia: loaded solid Topical lipid delivery nanoparticles and in against vitro evaluation 5-α reductase activity for the AKBABA 11th World H., Meeting EREL AKBABA Pharmaceutics, G., KANTARCI Biopharmaceutics A. G. Development and Evaluation of Monoclonal Antibody and Fragment-attached Pharmaceutical Technology, Solid Lipid 19-22 Nanoparticles March 2018 for KOTMAKÇI Targeted M., KARAGOZ Delivery to U., Cancer KANTARCI Cells A. G.

Development 2017 CRS Annual Meeting and Exposition, 16-19 July 2017 of glioblastoma of positive-charged solid lipid nanoparticles as sirna delivery systems for treatment EREL 2017 CRS AKBABA Annual G., Meeting AKBABA and H., KOTMAKÇI Exposition, M., 16 KANTARCI - 19 July 2017 A. G. Development of nucleic acid- of associated a device for magnetic regulating nanoparticles magnetic field with electromagnets for the in-vitro delivery AKBABA 2017 CRS H., Annual BAŞTÜRK Meeting O., KANTARCI and Exposition, A. G. An 16-19 July 2017 molecules optimized to NSCLC procedure cells to obtain extracellular vesicles for delivering STAT3-suppressing short RNA EREL 2017 CRS AKBABA Annual G., Meeting AKBABA and H., KOTMAKÇI Exposition, M., 16 KANTARCI - 19 July 2017 A. G. Biyobenzer KANTARCI A. ve G. Biyoüstün İlaç Kavramları, Kabul Kriterleri Arasındaki Farklar A IVEK-BİO 2017, 26 April 2017-29 January 2018 and Novel Magnetofection Synthesis Method of Cationic Lipid Coated Magnetic Nanoparticles MNPs Characterization AKBABA 1st International H., SELAMET Symposium; Y., KANTARCI Functional A. G. 31 March 2016 Nanomaterials in Industrial Applications: Academic Industry Meet, 29 - A Magnetofection novel synthesis metho of cationic lipid coated magnetic nanoparticles MNPs Characterization and AKBABA Functional H., nanomaterials SELAMET Y., KANTARCI in industrial A. applications, G. Solid 29-31 March 2016 androgenic lipid nanoparticle alopecia mediated gene silencing of 5 alpha reductase 2 for the treatment of AKBABA International H., EREL Multidisciplinary G., KANTARCI Symposium A. G. CYTOTOXICITY EVALUATION of MICROEMULSION on drug research FORMULATIONS and development, for ORAL Turkey, INSULIN 15-17 October DELIVERY 2014 EREL International G., AKBABA Multidisiplinary H., KANTARCI Symposium A. G. 2015 on Drug Research and Development, Eskişehir, Turkey, 15-17 October Non-viral androgenic shrna alopecia delivery system; Gene silencing of 5 alpha-reductase 2 for the treatment of EREL Collaborative G., AKBABA Congress H., KANTARCI of the European-Society-of-Gene-and-Cell-Therapy A. G. Therapy (FSGT), Helsinki, Finland, 17-20 September 2015, vol.26 (ESGCT) and Finnish-Society-of-Gene- Solid KOTMAKÇI lipid M., nanoparticles BOZOK ÇETİNTAŞ for gene V., ERTAN silencing G., KANTARCI in chemoresistant A. G. cancer cells Multiple ESGCT and FSGT Collaborative Congress, Helsinki, 17-21 September 2015 nanoparticles emulsion for gene can be targeting used as microreactors for synthesizing cationic lipid coated magnetic AKBABA ESGCT and H., FSGT SELAMET Colloborative Y., KANTARCI Congress A. G. Development of non toxic cationic lipid Helsinki, coated Finland, 17-20 September 2015 a novel method magnetic nanoparticles MNP s for gene delivery with AKBABA 1 st European H., UĞUR Conference K., SELAMET of Pharmaceutics Y., KANTARCI Fransa, A. G. In Reims, 13-14 April 2015 EREL vivo G., evaluation KOTMAKÇI M., of SÖZER rh insulin KARADAĞLI loaded L. microemulsion S., KANTARCI A. as G. oral delivery system

Size 1 st European Conference of Pharmaceutics, Fransa, Reims, 13-14 April 2015 diagrams variation of solid lipid nanoparticles prepared from various points of hot microemulsion phase KOTMAKÇI 2014 FIP World M., KANTARCI Congress, A. Bangkok, G. Preparation of dna delivery systems Thailand, for dermal 31 August gene 2014, delivery pp.1 Karagöz 2014 FIP U., World KOTMAKÇI Congress, M., AKBABA Bangkok, H., Thailand, KANTARCI 31 August A. G. Determining 2014, pp.1 KOTMAKÇI M., antimicrobial Öztürk İ., KANTARCI potential A. G., of ERMERTCAN novel mitomycin Ş. C-loaded microemulsion systems Cytotoxicity 24th European Study Congress Cationic of Clinical Solid Microbiology Lipid Nanoparticles and Infectious as Diseases, DNA Delivery Barcelona, System Spain, 10 May 2014, pp.1-2 AKBABA 8. Uluslararası H., KOTMAKÇI Katılımlı Türk M., Demir Toksikoloji Dora D., Derneği KORKMAZ Kongresi, C., KANTARCI Antalya, Turkey, A. G. Preparation of microemulsion systems for carbamazepine delivery 15 November 2012, pp.33 KOTMAKÇI AAPS Annual M., Meeting KANTARCI and A. Exposition G. Solid 2012, Chicago, United States Of America, 14 October 2012, pp.1 Diagram, Lipid and Nanoparticles Size Quality from of Selected Hot Microemulsions: Formulations a Method to Screen Hot Pseudoternary Phase KOTMAKÇI 16th International M., KANTARCI Pharmaceutical A. G. Development of novel cationic Technology solid lipid Symposium nanoparticles 2012, as Antalya, gene delivery Turkey, 10 system: September Characterization 2012, pp.186-189 and AKBABA transfection H., Kotmakchiev ability European Biotechnology Congress, M., Dora D. İstanbul, D., KORKMAZ Turkey, C., 28 Kantarci September G. Development - 01 October 2011, vol.22 method as DNA of delivery novel precirol system based cationic solid lipid nanoparticles by microemulsion dilution Kotmakchiev European Biotechnology M., AKBABA Congress, H., Dora D. İstanbul, D., KORKMAZ Turkey, C., 28 Kantarci September G. Determining in vitro anticancer activity of mitomycin C loaded - 01 microemulsion October 2011, vol.22 Kotmakchiev European Biotechnology M., Cetintas V. Congress, B., Kantarci İstanbul, G. In Turkey, 28 September - 01 October 2011, vol.22 KOTMAKÇI vitro Study M., KANTARCI of Hemolytic A. G. Potential of Microemulsion Formulation for Intravenous Delivery IN IPSMPS2010, İzmir, Turkey, 24 June 2010, pp.99 OIL VITRO MICROEMULSION RELEASE AND IN VIVO GAMMA CAMERA IMAGING OF MITOMYCIN C- LOADED SOYBEAN KANTARCI 7th World Meeting A. G., KOTMAKÇI on Pharmaceutics, M., AŞIKOĞLU Biopharmaceutic M., Özkılıç H., and Ertan Pharmaceutical G., Güneri T. 2010, pp.1-2 Technology, Valletta, Malta, 08 March Mitomycin-C KANTARCI A. G. Loaded, KOTMAKÇI O/W M., Soybean Ertan G., Oil Güneri Microemulsion T. for Parenteral Delivery IN World Soybean Research Conference VIII, 2009, Beijing, China, 10 August 2009, pp.167 KOTMAKÇI VITRO RELEASE M., KANTARCI STUDY A. G. OF, Ertan MITOMYCIN G., Güneri C T. LOADED O/W MICROEMULSION FORMULATION Recombinational 2nd PharmSciFair 2009, Nice, France, 08 June 2009, pp.191 DEBELEÇ BÜTÜNER telomere B., KANTARCI elongation A. G., MCRAE in telomerase W., MASOLOGİTES deletion G., mutant MCEACHERN of Kluveromyces M., Topcu Z. lactis Anew 30th FEBS microcapsule congress and form 9th IUMB of ampicilin conference, and 1 amoxcycilin - 08 July 2005 AŞIKOĞLU M., ertan g., ÖZGÜNEY I., KARASULU H. Y., KANTARCI A. G.

The 4th International Postgraduate Research Symposium On Pharmaceutics, Ankara, Turkey, 12 July 1994, pp.1 Supported Projects KANTARCI GEN TAŞIYICI A. G. FORMÜLASYONLARIN, KARAGÖZ U., Project HAZIRLANMASI Supported by Higher VE FARKLI Education KANSER Institutions, HÜCRE KÜLTÜRLERİNDE ING4 GENİNİN AKTARIMI ETKİNLİĞİNİN AMACIYLA GÖSTERİLMESİ, KOTMAKÇI M., KANTARCI 2016-2019 FİLTRASYON KROMATOGRAFİSİ A. G., AKBABA YÖNTEMİYLE H., EREL HÜCRE AKBABA KÜLTÜRÜNDEN G., Project Supported EKSTRASELÜLER by Higher VEZİKÜL Education İZOLASYONUNUN Institutions, JEL GELİŞTİRİLMESİ, KANTARCI A. G., Project 2016-2019 5-? REDÜKTAZ ENZİMİNİN Supported SHRNA KODLAYAN by Higher Education PLAZMİD Institutions, DNA YÜKLÜ ANDROJENİK KATI LİPİD NANOPARTİKÜLLER ALOPESİNİN ÖNLENMESİ ARACILIĞIYLA AMACIYLA GEN KANTARCI İFADESİNİN A. G., Project BASKILANMASI, Supported 2014 by Higher - 2016 YAKLAŞIM YENİ BİR MANYETİK NANOPARTEKÜL Education ÜRETİM Institutions, YÖNTEMİ VE DNA MANYETİK TAŞIYICI SİSTEMLERE ALAN DÜZENLEMELERİ BİYOFİZİKSEL ALTINDA BİR MANYETOFEKSİYON, KANTARCI A. G. Project 2013 Supported - 2016 TAŞIYICI SİSTEMLERİN HAZIRLANMASI, by Higher 2013 Education - 2015 Institutions, DERMAL YOLLA DNA AKTARIMI AMACIYLA DNA KANTARCI MANYETİK A. NANOPARTİKÜLFORMÜLASYONLARIN G. Project Supported by Higher Education HAZIRLANMASI Institutions, VE DNA KARAKTERİZASYONU, TAŞIYICI SİSTEMLER 2011 OLARAK - 2014LİPİD YAPIDA KANTARCI NANOPARTİKÜLLERİN A. G. Project HAZIRLANMASI, Supported by Higher KAREKTERİZASYONU Education Institutions, VE MODEL MİKROEMÜLSİYON İLAÇ YÜKLEME TEKNİĞİYLE ÇALIŞMALARI, KATI 2011 LİPİD KANTARCI A. G. Project Supported by Higher Education Institutions, GEN TEDAVİSİ AMACIYLA DNA YÜKLÜ KATI - 2013 NANOPARTİKÜL FORMÜLASYONLARININ HAZIRLANMASI, 2009-2010 LİPİT KANTARCI HAZIRLANAN A. G. MITOMISIN-C, Project Supported YÜKLÜ by TAŞIYICI Higher SISTEMLERIN Education Institutions, ORGANIZMADA VÜCUT BIYODAĞILIMININ ORGANLARINA HEDEFLEME İNCELENMESI, AMACIYLA 2010 2008 - KANTARCI SURFAKTAN A. OLARAK G., Project ÇEŞİTLİ Supported ALKOLLERİN by Higher İNCELENMESİ Education Institutions, VE STABİL MİKROEMULSİYON MİKROEMÜLSİYONLARA FORMULASYONLARINDA ETKEN MADDE KO- YÜKLENEREK FORMÜLASYON GELİŞTİRİLMESİ ÜZERİNE ÇALIŞMALAR, 2000-2003 Patent Kotmakçı üretim düzeneği, M., Bozok üretim Çetintaş yöntemi V., Kantarcı ve uygulamaları, A. G., Ertan Patent, G., Düşük CHAPTER sürfaktan A Human içerikli, Needs, konsantre Initial katı Registration, lipid nanotanecikler: Akbaba H., Kantarcı A. G., Çoklu emülsiyonların mikroreaktör olarak kullanımı ile manyetik nanopartikül 2018 Patent, CHAPTER A Human Needs, Initial Registration, 2013 üretim yöntemi, Citations Total h-index Citations (WOS):7 (WOS):187