Nazim Serdar Turhal M.D. Present Academic Rank and Position: Marmara University Medical School

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Personal Information Nazim Serdar Turhal M.D. Date of Birth: April 5 th, 1964 Place of Birth: Eskisehir, Turkey Citizenship: T.R. / U.S.A. Work Address: Tophanelioglu cad. 13/15 Altunizade Istanbul 81190 Office: Unel Apt 251/5 Bagdat Cad Goztepe Istanbul 34728 Telephone: 90 (216) 3580238-39-40 (pbx) Fax: 90(216) 3580237 e-mail: turhal@superonline.com Present Academic Rank and Position: Professor, Director, Marmara University Medical School Dept. of Internal Medicine, Division of Oncology, Marmara University Hospital Education: September 1988 M.D. Univ. of Istanbul 1988-89 Visiting Extern U.C. San Francisco San Francisco, Ca. 1989-90 Surgical Intern Baptist Med. Ctr. Birmingham, Al. 1990-93 Internal Medicine Resident Griffin Hospital (Yale U. Affiliate) Derby, Ct. 1993-96 Hematology-Oncology Fellow Mt.Sinai Med. Center New York, N.Y. 1996-97 Bone Marrow Transplant Fellow Mt. Sinai Med. Center New York, N.Y. Board Certification: ECFMG: April 1989 428514-4 FLEX: June 1990 640405501 Internal Medicine (USA): November 1996 158365 Oncology (USA): November 1997 158365 Renewed November 2007 158365 Internal Medicine (Turkish) October 1996 42248-46399 Oncology (Turkish) August 1997 43335-46399 Oncology (European) January 2000

2 Medical Licensure New York 192309 Tennessee 034693 Honors: 2000 Technology Transfer Grant Recipient ESMO-NCI Milan 1994-95 Chief Fellow Mt. Sinai Med. Center 1987 Representative Class of '89 Warsaw, Poland 1986 Representative Class of '88 K. City, Kuwait 1981-82 American Field Service Student Nebraska, USA Previous Professional Positions and Appointments Outside of present position I covered numerous physicians and locations in United States for locum tenants appointments since 1997. Education-Teaching 1. Weekly junior medical student bed side teaching 3 hours 1997-present 2. Quarterly junior medical student oncology lectures 8 hours 1997-present 3. Biweekly Oncology seminars to fellows and residents 4 hours 1997-present 4. Weekly Cancer care meetings with nurses, residents, fellows, psychologists 4 hours 1997-present 5. Weekly junior medical student modular educational activities 48 hours 1999-present Postdoctoral Fellows Working or Worked For Me Gul Atalay M.D. 6 years Med. Oncology Faysal Dane 4 years Med. Oncology Devrim Cabuk 2 years Med. Oncology Mehmet Teomete 2 years Med. Oncology Mahmut Gumus 3 years Med. Oncology Mehmet Aliustaoglu 3 years Med. Oncology Meltem Ekenel 3 years Med. Oncology Salih İyikesici 3 years Med. Oncology Hatice Yildiz 1 year Data Management Esen Guzet 2 years Data Management Neslihan Doygun 2 years Data Management Fatih Ergun 2 years Data Management Sibel Çelebioğlu 1 year Data Management

3 Institutional, Departmental, and Divisional Administrative Responsibilities, Committee Memberships, and Other Activities Director Division of Oncology 1998-present Credentialing Coordinator Department of Medicine 2000-present Faculty of Pharmacy Medical Lectures Coordinator Medical School 2000 Transfusion Committee Marmara Univ. Hospital 1999 Hospital Formulary Marmara Univ. Hospital 1999 Professional and Society Memberships American Society of Clinical Oncology 1999 European Society of Medical Oncology 1999 Balkan Union of Oncology 1998 American College of Physicians 1998 Turkish Oncological Society 1998 Intramural Presentations 1. Weekly Cancer Grand Rounds 1 hour 1998-2. Weekly multidisciplinary patient care meetings 3 hours 1998-3. Weekly oncological pathology meetings 2 hours 1998-4. Quarterly Internal Medicine grand rounds 1 hour 1998-5. Weekly Thoracic malignancies multidisciplinary patient care meetings 2 hours 1999-6. Oncology Nursing Regional Conference 31 hours 2000 7. Surgical Oncology Nursing PhD Program 12 hours 2000 8. Oncology Nursing National Conference 32 hours 2001 Clinical Practice, Interests and Accomplishments Active member of EORTC Gastrointestinal tumors study group. Research Interests Prognostic factors and therapy in Gastrointestinal malignancies Research Grants Awarded 1. Marmara University research grant for mamosintigraphy project 2. European Society for Medical Oncology Technology Transfer grant Community Activities 1. Living with Cancer television series at Medical Channel 2001-02 2. Living with Cancer column at weekly Gazette Kadikoy 2001-03

4 Bibliography International Peer Reviewed Journal Publications: 2.3.1.1. Turhal N, Sullivan MB, Blakemore WS. Thyroglossal Duct Cyst. South Med J, 1990, 83:8, 983-4. 2.3.1.2. Turhal N, DeLuca VA Jr. Ulcerative Colitis and Scleroderma. A coincidental relationship. J Clin Gastroenterol. 1994, 18:3, 218-9. 2.3.1.3. Turhal NS, Henehan MD, Kaplan KL. Multiple myeloma: a patient with unusual features including intracranial and meningeal involvement, testicular involvement, organomegaly, and plasma cell leukemia. Am J Hematol 1998, 57:1, 51-56. 2.3.1.4. Turhal NS. Cyclosporin A and Imipenem Associated Seizure Activity in Allogeneic Bone Marrow Transplantation Patients. Journal of Chemotherapy 1999 11(5): 410-413. 2.3.1.5. Turhal NS, Erdal S, Karacay S. Efficacy of the Treatment to Relieve Mucositis Induced Discomfort. Supportive Care in Cancer 2000 8(1): 55-58. 2.3.1.6. Turhal NS. Pancreatic Duct Cell Carcinoma with Positive In-111 Octreotide Uptake. Journal of Experimental and Clinical Cancer Research 2000 19(2): 241-244. 2.3.1.7. Turhal NS. Sumatriptan overdose in episodic cluster headache: a case report of overuse without event. Cephalalgia. 2001 21:700. 2.3.1.8. Turhal NS, Rand J. Antiphospholipid syndrome in HIV infection - Report of four cases and review of literature. Allergy & Clinical Immunology International 2001 13(6):1-4. 2.3.1.9. Duman D, Turhal NS, Duman DG, M.D. Fatal Aplastic Anemia during Treatment with Ketoconazole. American Journal of Medicine 2001, 111:9 2.3.1.10. Turhal NS. Two cases of advanced renal cell cancer with prolonged survival of 8 and 12 years. Japanese Journal of Clinical Oncology 2002 32(4): 152-153 2.3.1.11. Turhal NS, Gumus M, Atalay G, Aliustaoglu M, Kabakas F, Karamanoglu A, Sengoz M. Outpatient cancer care in a Turkish university hospital. Journal of BUON 2002 7(4): 397-398. 2.3.1.12. Turhal NS, Efe B, Gumus M, Aliustaoglu M, Karamanoglu A, Sengoz M. Patient satisfaction in the outpatients` chemotherapy unit of Marmara University, Istanbul, Turkey: a staff survey. BMC Cancer 2002 2(1): 30-33. 2.3.1.13. Turhal NS, Aliustaoglu M, Gurses I, Gumus M, Atalay G, Karamanoglu A, Sengoz M. Neoplastic diseases prevalence in a Turkish university hospital. Journal of BUON 2003 8(1): 45-48. 2.3.1.14. Karamanoglu A, Yumuk PF, Gumus M, Aliustaoglu M, Selimen D, Sengoz M, Turhal NS. Port needles: Do they need to be removed as frequently in infusional chemotherapy? Journal of Infusional Nursing 2003 26(4):239-242. 2.3.1.15. Abacıoglu U, Sengoz M, Yumuk F, Salepci T, Turhal NS. Cisplatin and etoposide in extra pulmonary small cell cancer. Tumori 2003 89(3): 274-277. 2.3.1.16. Yumuk PF, Abacioglu U, Caglar H, Gumus M, Sengoz M, Turhal NS. Outcome of

5 rectum and sigmoid carcinoma patients receiving adjuvant chemoradiotherapy in Marmara University Hospital. J Chemother 15 (6): 603-606, 2003. 2.3.1.17. Turhal NS, Dane F, Dede F, Gumus M, Yumuk PF, Cakalagaoglu F, Savcı D, Karaman M, Gulluoglu B, Turoglu HT. 99m-Tc-MDP Scintimammography to assess angiogenesis in patients with untreated breast cancer. Anticancer Research. 24:1999-2006 (2004) 2.3.1.18. Yumuk PF, Gumus M, Ekenel M, Basaran G, Aliustaoglu M, Topal A, Turhal NS, N. Attitude Toward Genetic Testing in Turkish Society. Genetic Testing 8(2):169-173, 2004 2.3.1.19. Yumuk PF, Aydin SZ, Dane F, Gumus M, Ekenel M, Aliustaoglu M, Karamanoglu A, Sengoz M, Turhal NS. The absence of early diarrhea with atropine premedication during irinotecan therapy in metastatic colorectal patients. International Journal of Colorectal Disease 19: 609-610, 2004. 2.3.1.20. Bolukbas FF, Kılıc H, Bolukbas C, Gumus M, Horoz M, Turhal NS, Kavalı B. Serum leptin concentration and advanced gastrointestinal cancers: a case controlled study. BMC Cancer 2004, 4:29-32. 2.3.1.21. Yumuk PF, Abacioglu U, Demir G, Cabuk D, Dane F, Gumus M, Ozguroglu M, Ekenel M, Basaran G, Turhal NS. Does the Incidence of Anal Canal Cancers Differ in Moslem Societies? International Journal of Colorectal Disease, Clinical and Molecular Gastroenterology and Surgery. 20(1), 76 2004. 2.3.1.22. Aliustaoglu M, Yumuk PF,Gumus M, Ekenel M, Bolukbas F, Mutlu N, Basaran G, Avsar E, Turhal NS. D-Dimer Can it be a marker for malignant gastric lesions. Acta Oncologica, 2004 Dec 43(8) 770-771. 2.3.1.23. Blazeby JM, Conroy T, Bottomley A, Vickery C, Arraras J, Sezer O, Moore J, Koller M, Turhal NS, Stuart R, Van Cutsem E, D Haese S, Coens C. Clinical and Psychometric validation of a questionnaire module, The EORTC QLQ-STO 22, to assess quality of life in patients with gastric cancer. Eur J Cancer, 2004 Oct 40(15): 2260-8 2.3.1.24. Gumus M, Yumuk PF, Atalay G, Aliustaoglu M, Macunluoglu B, Dane F, Caglar H, Sengoz M, Turhal S. What should be the optimal number of lymph nodes dissected in colorectal Cancer surgery? Tumori, 172/03. 11 2004. 2.3.1.25. Yumuk PF, Turhal NS, Gumus M, Hatabay NF, Turken O, Ozkan A, Salepci T, Aliustaoglu M, Ahiskali R, Results of paclitaxel (day 1 and 8) and Carboplatin given on every three weeks in advanced (stage III-IV) non-small cell lung Cancer, BMC Cancer, (MS:7372801141679098), 2005 March, 21 2.3.1.26. Abacioğlu U, Yumuk PF, Caglar H, Sengoz M, Turhal NS, Concurrent chemoradiotherapy with low dose weekly Gemcitabine in stage III non-small cell lung cancer. BMC Cancer. 2005 Jul, 6;5:71 2.3.1.27. Yumuk PF, Turhal NS, Gumus M, Hatabay NF, Turken O, Ozkan A, Salepci T, Aliustaoglu M, Ahiskali R. Results of Paclitaxel (day 1 and 8) and carboplatingiven on every three weeks in advanced (stage III-IV) non-small cell lung cancer. BMC Cancer. 2005 Jan 25;5:10. 2.3.1.28. Yumuk PF, Abacioglu U, Demir G, Cabuk D, Dane F, Gumus M, Ozguroglu M, Ekenel M, Basaran G, Turhal NS, Does the incidence of anal canal cancers differ in Moslem societes? International Journal of Colorectal Disease 2005 20:76

6 2.3.1.29. Turhal NS, Popov I. Colorectal cancer care in the Balkan countries. Journal of Balkan Union of Oncology Volume 10 No: 2, April-June 2005 189-193 2.3.1.30. Gumus M, Yumuk PF, Atalay G, Aliustaoglu M, Macunluoglu B, Dane F, Caglar H, Sengoz M, Turhal NS, What is the optimal number of lymph nodes to be dissected in colorectal cancer surgery? Tumori. 2005 Mar-Apr;91(2): 168-72 2.3.1.31. Abacioglu U, Yumuk PF, Caglar H, Sengoz M, Turhal NS, Concurrent chemoradiotherapy with low dose weekly gemcitabine in stage III non-small cell lung cancer. BMC Cancer, 2005 Jul 6;5:71 2.3.1.32. Onol FF, Tanidir Y, Kotiloglu E, Bayramicli M, Turhal NS, Turkeri LN. Proximal type epithelioid sarcoma of the scrotum: a source of diagnostic confusion that needs immediate attention. Eur Urol. 2006 Feb; 49(2):7. Epub 2005 Nov 7. 2.3.1.33. Turhal NS, Popov IP. Colorectal cancer care in the Balkan countries. J BUON 2005 Apr-Jun;10(2):189-93 2.3.1.34. Onol FF, Tanidir Y, Kotiloglu E, Bayramicli M, Turhal NS, Turkeri LN. Proximal type epithelioid sarcoma of the scrotum: a source of diagnostic confusion that needs immediate attention: Part 2. Eur Urol 2006 Mar 49(3):578-80. 2.3.1.35 Gumus M, Yumuk PF, Salepci T, Aliustaoglu M, Dane F, Ekenel M, Basaran G, Kaya H, Barisik N, Turhal NS. HPV DNA frequency and subset analysis in human breast cancer patients normal and tumoral tissue samples. J Exp Clin Cancer Res. 2006 Dec;25(4):515-21. 2.3.1.36. Onol FF, Tandr Y, Kotiloglu E, Bayramicli M, Turhal NS, Turkeri LN. Proximal type epithelioid sarcoma of the scrotum: a source of diagnostic confusion that needs immediate attention. Part 1: Eur Urol 2006 Feb;49(2): 406-7 2.3.1.37. Onol FF, Tandr Y, Kotiloglu E, Bayramicli M, Turhal NS, Turkeri LN. Proximal type epithelioid sarcoma of the scrotum: a source of diagnostic confusion that needs immediate attention. Part 2: Eur Urol. 2006 Mar; 49(3):578-80. 2.3.1.38. Gumus M, Yumuk PF, Salepci T, Aliustaoglu M, Dane F, Ekenel M, Basaran G, Kaya H, Barisik N, Turhal NS. HPV DNA frequency and subset analysis in human breast cancer patients normal and tumoral tissue samples. Journal of Experimental and Clinical Cancer Research, December 2006, 515-521 2.3.1.39. Komurcu S, Turhal NS, Altundag K, Atahan L, Turna HS, Manavoglu O, Yavuz AA, Ozkok S, Aliustaoglu M, Altinbas M, Pak Y, Cooper R, Yaylaci M, Demirkan B, Sarihan S, Ozdemir F. Safety and efficacy of transdermal fentanyl in patients with cancer pain: phase IV, Turkish Oncology group trial. Eur J Cancer Care (Engl). 2007 Jan; 16(1):67-73 2.3.1.40. Atasoy BM, Abacioglu U, Dane F, Ozgen Z, Yumuk PF, Ozden S, Akgun Z, Mayadagli A, Basaran G, Turhal NS, Sengoz M. Concomitant administration of uracil-tegafur and leucovorin during adjuvant radiotherapy for locally advanced rectal cancer. J BUON. 2007 Apr- Jun;12(2):203-8.

7 2.3.1.41. Celikel C, Eren F, Gulluoglu B, Bekiroglu N, Turhal NS. Relation of neuroendocrine cells to transforming growth factor-alpha and epidermal growth factor receptor expression in gastric adenocarcinomas: prognostic implications. Pathol Oncol Res. 2007:13(3):215-26. Epub 2007 Oct 7. 2.3.1.42. Cabuk D, Basaran G, Celikel C, Dane F, Yumuk PF, Iyikesici MS, Ekenel M, Turhal NS. Vascular Endothelial Growth Factor, Hypoxia-Inducible Factor 1 Alpha and CD34 Expressions in Early-Stage Gastric Tumors: Relationship with Pathological Factors and Prognostic Impact on Survival. Oncology. 2007 Nov 15;72(1-2):111-117. 2.3.1.43. Atasoy BM, Abacioglu U, Dane F, Ozgen Z, Yumuk PF, Ozden S, Akgun Z, Mayadagli A, Basaran G, Turhal NS, Sengoz M. Concomitant administration of uracil-tegafur and leucovorin during adjuvant radiotherapy for locally advanced rectal cancer. Journal of BUON 12: 203-208, 2007 2.3.1.44. Yumuk PF, Dane F, Yumuk VD, Yazici D, Ege B, Bekiroglu N, Toprak A, Iyikesici S, Basaran G, Turhal NS.Impact of body mass index on cancer development. J BUON. 2008 Jan- Mar;13(1):55-59 2.3.1.45. Atasoy BM, Dane F, Yumuk PF, Akgün Z, Turhal NS, Abacioğlu U, Sengöz M. Toxicity and feasibility analysis for cisplatin-based concomitant chemoradiotherapy in locally advanced nasopharyngeal carcinoma. J BUON. 2008 Jan-Mar;13(1):43-50. 2.3.1.46. Koldas M, Gumus M, Seker M, Seval H, Huyla K, Dane F, Kural A, Gumus A, Salepci T. and NS Turhal, Thrombin-activatable fibrinolysis inhibitor levels in patients with non-smallcell lung cancer, Clin Lung Cancer., 9(2), 112-115 (2008). 2.3.1.47. Ustaalioglu BB, Gumus M, Bilici A, Seker M, Dane F, Salepci T, S alman T, Aliustaoglu M, Gezen C, Yaylaci M, Turhal NS, Neoadjuvant chemotherapy for locally advanced breast cancer: a single center experience. Med. Oncol, 2009 Jun 2. 2.3.1.48. Kefeli U, Dane F, Yumu k PF, Karamanoglu A, Iyikesici M, Basaran G, Turhal NS, Prolonged interval in prophylactic heparin flushing for maintenance of subcutaneous implanted port care in patients with cancer. Eur J Cancer Care (Engl), 2009 Mar; 18(2), 191-4. 2.3.1.49. Kuscu MK, Dural U, Onen P, Yasa Y, Yayla M, Basaran G, Turhal NS, Bekiroglu N. The association between individual attachment patterns, the perceived social support, and the psychological well-being of Turkish informal caregivers. Psychooncology, 2009 Jan 12. 2.3.1.50. Dane F, Ozturk MA, Tecimer T, Atasoy BM, Cabuk D, Yumuk PF, Basaran G, Teomete M, Turhal NS. A case of Kikuchi-Fujimoto disease misdiagnosed as Hodgkin s lymphoma: The importance of second opinion. J BUON, 2009 Apr-Jun;14(2):309-11. 2.3.1.51. Kefeli U, Dane F., Yumuk PF, Karamanoglu A, Iyikesici S, Basaran G, and NS Turhal, Prolonged inerval in prophylactic heparin flushing for maintenance of subcutaneous implanted port care in patients with cancer, Eur J Cancer Care (Engl), 18(2), 191-194 (2009). 2.3.1.52. Dane F, Ozturk MA, Tecimer T, Atasoy BM, Cabuk D, Yumuk PF, Basaran G, Teomete M, and NS Turhal, A case of Kikuchi-Fujimoto disease misdiagnosed as Hodgkin s lymphoma: the importance of second opinion, J BUON, (2009). [basımda]

8 2.3.1.53. Gumus M, Basak O, Ustaalioglu MG, Kiziltan E, Bilici A, Seker M, Erkol B, Salepci T, Mayadagli A, Turhal NS. Factors that Affect Patients Decision-Making about Mastectomy or Breast Conserving Surgery, and the Psychological Effect of this Choice on Breast Cancer Patients. Breast Care 2010;5:164 168 2.3.1.54. Dane F, Yumuk PF, Başaran G, Gündüz F, Peker Ö, Turhal NS, A Case of Primary Breast Mantle Cell Lymphoma with Atypical Relapse Patterns and Rewiew of the Literature Journal of BUON Vol: 16 No: 2, 2010 2.3.1.55. Turhal NS, Bas E, Er O, Aliustaoglu M, Seber S, Dane F, Korkmaz T, Soyuer I, Ozkara S, Celikel C. ERCC1 is not expressed in hepatocellular cancer: A Turkish Oncology Group, Gastrointestinal Oncology Subgroup study. Journal of BUON 15: 794-796, 2010 2.3.1.56. Turhal NS. Dane F, Sınav H, Yalçın N, Khorshidi Z, Yalçın ZZ. Anxiety and depression in Turkish breast cancer patients. Journal of BUON 15: 720-725, 2010 2.3.1.57. Korkmaz T, Seber S, Turhal NS. Primary melanoma of the gallbladder. Letter 802 2.3.1.58. Basaran G, Cabuk D, Caglar HB, Gulluoglu B, Kaya H, Seber S, Korkmaz T, Telli F, Kocak M, Dane F, Yumuk PF, Turhal NS. Clinical outcome of breast cancer patients with N3a ( 10 positive lymph nodes) disease: has it changed over years? Med Oncol. 2010 Apr 14. [Epub ahead of print] DOI 10.1007/s12032-010-9516-1. 2.3.1.59. Dane F, Ozturk MA, Gumus M, Guven A, Aliustaoğlu M, Cabuk D, Teomete M, Basaran G, Yumuk PF, Turhal NS. Effi cacy, safety and prognostic features of resected colon carcinoma treated in real world practice: a retrospective cohort-study. Journal of BUON 16: 257-264, 2011 2.3.1.60. Bilici A, Dane F, Seker M, Ustaalioglu BB, Aliustaoglu M, Temiz S, Gezen C, Yavuzer D, Aksu G, Mayadagli A, Gumus M, Uygun K, Turhal NS. Is Subdivision of pt2 Tumors Superior to Lymph Node Metastasis for Predicting Survival of Patients with Gastric Cancer? Review of 224 Patients from Four Centers. Digestive Diseases And Scienses DOI: 10.1007/s10620-011-1721-z 2011. 2.3.1.61. Dane F, Akif Ozturk M, Gumus M, Guven A, Aliustaoglu M, Cabuk D, Teomete M, Basaran G, Fulden Yumuk P, Turhal NS. Efficacy, safety and prognostic features of resected colon carcinoma treated in "real world" practice: a retrospective cohort-study. J BUON. 2011 Apr-Jun;16(2):257-64. 2.3.1.62. Basaran G, Devrim C, Caglar HB, Gulluoglu B, Kaya H,Seber S, Korkmaz T, Telli, Kocar M, Dane F, Turhal NS. Clinical outcome of breast cancer patients with N3a ( 10 positive lymph nodes) disease: has it changed over years? Medical Oncology: Volume 28, Issue 3 (2011), Page 726-732. 2.3.1.63. Korkmaz T, Seber S, Basaran G, Yumuk PF, Dane F, Kocar M, Telli F, Turhal NS. 5- Flourouracil Induced Encephalopathy in Parkinson s disease. International Journal of Hematology and Oncology 2011 vol: 21 Num 1 Page(s): 001-003 2.3.1.64. Abali H, Ata A, Ozdogan M, Turhal NS, Cabuk D, Seyrek E, Coskun HS, Arik Z, Erman M, Celik I. Frequency of comorbid illnesses in cancer patients in Turkey. Journal of BUON 16: 557-560, 2011. 2.3.1.65. Turhal NS, Dane F, Butur S, Kocak M, Telli F, Seber S, Kanitez M, Aktas B, Yumuk PF. Efforts to Validate the Applicability of Established Chemotherapy Treatment in Turkish Cancer Patient. Pharmaceutica Analytica Acta. S14. 2011.

9 2.3.1.66. Okutur K, Korkmaz T, Seber S, Dane F, İlhan M, Turnal NS, Demir G. Weekly Docetaxel, Cisplatin and 5-Flourouracil in the first-line treatment of metastatic gastric cancer. MOJ:1;35-40, 2011. 2.3.1. 67. Turhal NS. Daily life of a Turkish Medical Oncologist. J Oncol Pract 8:164-166, 2012 2.3.1.68. Korkmaz T, Seber S, Okutur K, Basaran G, Yumuk F, Dane F, Oney T, Polat O, Madenci O, Demir G, Turhal NS. Serum thymidine kinase 1 levels correlates with FDG uptake and prognosis in patients with non small cell lung cancer. Biomarkers, 2012; Early Online: 1 7 2012 Informa UK, Ltd. 2.3.1.69. Turhal NS et al. The Association between Socio-Demographic Parameters and the Use of Complementary Interventions in Cancer Patients in Turkey A Turkish Oncology Group Study. Journal of Cancer Therapeutics and Research, ISSN: 2049-7962, Volume: 1, Issue: 1, 2012 2.3.1.70. Uncu D, Aksoy S, Cetin B, Yetisyigit T, Ozdemir N, Berk V, Dane F, İnal A, Harputluoglu H, Budakoglu B, Koca D, Sevinc A, Cihan Ş, Durnalı AG, Ozkan M, Oztürk M, Işıkdoğan A, Büyükberber S, Benekli M, Köş T, Alkış N, Karaca H, Turhal NS, Zengin N. Anatolian Society of Medical Oncology. Results of Adjuvant FOLFOX regimens in stage III. Colorectal Cancer Patients. Retrospective Analysis of 667 Patients. Oncology 2013.84:240 245 2.3.1.71. Korkmaz T, Seber S, Yavuzer D, Gumus M, Turhal NS. Primary renal carcinoid: Treatment and prognosis. Critical Reviews in Oncology/Hematology-2013 ONCH-1712; No of pages 19. 2.3.1.72. Artac M, Turhal NS, Kocer M, Karabulut B, Bozcuk H, Yalcin S, Karaagac M, Gunduz S, Isik N, Uygun K. Do high-risk features support the, use of adjuvant chemotherapy in stage II colon cancer? A Turkish Oncology Group study. Tumori, 100:143-148, 2014 2.3.1.73. Kani HT, Siykhmbayev A, Demircan N, Banzragch M, Gunes Yegin E, Bicakci Y, Aydin Y, Irmak R, Guney Duman D, Yumuk PF, Dane F, Turhal NS, Bekiroglu N, Ozdogan OC. Benefıcıal Effect of Multıdıscıplınary approach on Survıval ın Hepatocellular Carcınoma Patıents. Journal of Hepatology2014 vol 60. S215-S359, P577. 2.3.1.74. Kocar M, Bozkurtlar E, Telli F, Turhal NS, Kaya H, Kocar H, Yumuk PF. PTEN loss is not associated with trastuzumab resistance in metastatic breast cancer. JBUON 2014; 19(4): 900-905. 2.3.1.75. Yalcin S, Trad D, Yasser AK, Halawani H, Demir OG, Mall R, Meshcheryakov A, Nasr F, Nosworthy A, Osinsky D, Tumanova A, Turhal NS, Tejpar S, Köhne CH. Personalized treatment is beter than one treatment fits all in the management of patients with mcrc: a consensus statement. Future Oncol 2014; 10(16), 2643-2657 2.3.1.76. Tanriverdi O, Yavuzsen T, Akman T, Senler FC, Taskoylu BY, Turhal NS, Komurcu S, Cehreli R, Yaren A, Ozyilkan JCED: Your manuscript entitled The perspective of non-oncologistphysicians on patients with metastatic cancer and palliative care (ALONEStudy): a study of the Palliative Care Working Committee of the Turkish Oncology Group (TOG). J Cancer Educ. 2015 Jun;30(2):253-9. doi: 10.1007/s13187-015- 0794-3. PMID: 25631655 [PubMed - in process] 2.3.1.77 Dede F, Civen H, Dane F, Aliustaoglu M, Turhal NS, Turoglu HT, İnanir S. Carbon-14 urea breath test: does it work in patients with partial gastric resection? Ann Nucl Med. 2015 Nov;29(9):786-91. doi: 10.1007/s12149-015-1005-3. Epub 2015 Jul 18. PMID: 26187581 [PubMed - in process]

10 2.3.1.78. Ozturk MA, Dane F, Karagoz S, Tural D, Selcukbiricik F, Demirelli F, Buyukunal E, Ozguroglu M, Turna H, Erdamar S, Celikel CA, Bozkurtlar EB, Yumuk PF, Mandel NM, Turhal NS, Serdengecti S. Is perineural invasion (PN) a determinant of disease free survival in early stage colorectal cancer? Hepatogastroenterology. 2015 Jan- Feb;62(137):59-64. PMID: 25911868 [PubMed - indexed for MEDLINE] 2.3.1.79. Ozturk MA, Dane F, Karagoz S, Tural D, Selcukbiricik F, Demirelli F, Buyukunal E, Ozguroglu M, Turna H, Erdamar S, Celikel CA, Bozkurtlar EB, Yumuk PF, Mandel NM, Turhal NS, Serdengecti S. Epidemiology of colorectal cancer in Turkey: A crosssectional disease registry study (A Turkish Oncology Group trial). Turk J Gastroenterol. 2015 Mar;26(2):145-53. doi: 10.5152/tjg.2015.5685. PMID: 25835113 [PubMed - indexed for MEDLINE] 2.3.1.80. Tanriverdi O, Yavuzsen T, Turhal NS, Kilic D, Yalcin S, Ozkan A, Uzunoglu S, Uysal- Sonmez O, Akman T, Aktas B, Ulger S, Babacan T, Komurcu S, Yaren A, Cay-Senler F. Depression and socio-economical burden are more common in primary caregivers of patients who are not aware of their cancer: TURQUOISE Study by the Palliative Care Working Committee of the Turkish Oncology Group (TOG). Eur J Cancer Care (Engl). 2015 Mar 30. doi: 10.1111/ecc.12315. [Epub ahead of print] PMID: 25828949 [PubMed - as supplied by publisher] 2.3.1.81. Tanriverdi O, Cay-Senler F, Yavuzsen T, Turhal NS, Akman T, Komurcu S, Cehreli R, Ozyilkan O. Perspectives and practical applications of medical oncologists on defensive medicine (SYSIPHUS study): a study of the Palliative Care Working Committee of the Turkish Oncology Group (TOG). Med Oncol. 2015 Apr;32(4):106. doi: 10.1007/s12032-015-0555-5. Epub 2015 Mar 7. PMID: 25750041 [PubMed - in process]

11 National (Turkish) Publications: 2.3.2.1. Turhal NS. Metastatik meme kanseri yaygın kemik metastazlarında tedavi, Kanser Gündemi, Türkiye Kanserle Savaş Vakfı, 1998 3(3): 118-121. 2.3.2.2. Turhal NS. Yetişkin kanser hastalarında transfüzyon tedavisi yaklaşımları Damla, Kan Merkezleri ve Transfüzyon Derneği Bülteni, 1998 22:4-7. 2.3.2.3. Turhal NS. Meme kanserinin biyolojik tedavisinde: Herceptin, Academic Hospital 1998 4:16-18. 2.3.2.4. Turhal NS, Tanju P, Pekin S. Serviks kanseri etyolojisine yönelik standart ve gelecek vadeden tarama yaklaşımları Hekimler Birliği Vakfı, Türkiye Klinikleri, Jinekolojik Obstetrik, 1999 9(3): 215-220. 2.3.2.5. Turhal NS, Akdas A. Prostat kanserinde gen tedavisi uygulaması ve sorunları Üroloji Bülteni 1999 10(1): 5-11. 2.3.2.6. Turhal NS. Lokal ileri evre meme kanserinde neoadjuvan ve adjuvan kemoterapi Hematoloji-Onkoloji, Güncel Derleme Dergisi, 2001 3(2):123-127. 2.3.2.7. Atalay G, Turhal NS. Kanserli hastalarda ağrı dışı semptomların palyasyonu: Hıçkırık, disfaji ve dispepsi Hematoloji-Onkoloji, Güncel Derleme Dergisi, 2001, 3(3): 236-239. 2.3.2.8. Kaya H, Kotiloglu E, Sengoz M, Turhal S, Uneri C. Aggressive fibromatosis: A case report. Journal of Marmara University Dental Faculty, 2001 Vol 4(3): 288-90. 2.3.2.9. Basaran G, Ekenel M, Demirkalem P, Cakır T, Gulluoglu B, Gumus M, Dane F, Iyikesici S, Kaya H, Yumuk PF, Turhal NS. Evre 1 (T1 N0 M0) Meme Kanseri: Patolojik özellikler ve klinik sonuçlar, Türk Onkoloji Dergisi, 2004 19(2):53-57. 2.3.2.10. Yumuk PF, İyikesici MS, Gumus M, Aliustaoglu M, Dane F, Basaran G, Ekenel M, Abacıoglu U, Turhal NS. Lokal ileri ve metastatik küçük hücreli dışı akciğer kanseri hastalarının değerlendirilmesi, Marmara Üniverstesi deneyimi, Türk Onkoloji Dergisi, 2004 19(3): 106-110. 2.3.2.11. Yumuk PF, Turhal NS. Bir medikal onkolog perspektifinden muskuloskeletal hastalıklarda nükleer tıp Turkish Journal of Nuclear Medicine 2004, Baskıda 2.3.2.12. Atasoy BM, Dane F, Sarı M, Yumuk PF, Akgün Z, Turhal NS, Abacıoğlu U, ve Şengöz M, Lokal ileri evre skuamöz hücreli baş ve boyun kanserinde sisplatinle eş zamanlı kemoradyoterapi: Yan etki ve uygulanabilirlik analizi, Türk Onkoloji Dergisi, 23, 1-11 (2008). 2.3.2.13. Atasoy BM, Dane F, Çağlar H, Tezcanlı E, Cingi A, Abacıoğlu U, Turhal NS, ve C Yeğen, Rezeke edilebilir lokal ileri evre rektum kanserinde floroprimidin bazlı

12 kemoterapi ile eş zamanlı ameliyat öncesi radyoterapi, Türk Onkoloji Dergisi, 23, 163-171 (2008). 2.3.2.14. Atasoy BM, Dane F, Kefeli AÜ, Caglar H, Cingi A, Turhal NS, Abacıoglu U, Yegen C. Concomitant chemoradiotherapy with low-dose weekly Gemcitabine for nonmetastatic unresectable pancreatic cancer. The Turkish Journal of Gastroenterology 2011;22(1):60-64

13 Citations: 2.3.3.1. Author(s): Kim JH; Lee SH; Park J; Kim HY; Lee SI; Nam EM; Park JO; Kim K; Jung CW; Im YH; Kang WK; Lee MH; Park K. Title: Extrapulmonary small-cell carcinoma: a single-institution experience. Source: JAPANESE JOURNAL OF CLINICAL ONCOLOGY 2004, Vol 34, Iss 5, pp 250-254 2.3.3.2. Yao JL, Madeb R, Bourne P, Lei J, Yang X, Tickoo S, Liu Z, Tan D, Cheng L, Hatem F, Huang J, Anthony S. Title: Small Cell Carcinoma of the Prostate: An Immunohistochemical Study. Source: American Journal of Surgical Pathology. 30(6):705-712, June 2006 2.3.3.3. Author(s): D. Demellawy, A. Samkari, M. Sur, F. Denardi, S. Alowami. Title: Primary small cell carcinoma of the cecum. Source: Annals of Diagnostic Pathology, Volume 10, Issue 3, Pages 162-165 2.3.3.4. Author(s): Young HK, Ryuk K, Ghap JJ, Myung HR, Sang YH, Hyuk CK, Jin SJ, Tae BS, Jong YO, Ki NL. Title: Extrapulmonary small-cell carcinoma of the liver Source: Journal of Hepato-Biliary-Pancreatic Surgery Oct. 2004 Vol 11, Num 5, 2.3.3.5. Author(s): Vogelsang H., Siewert I.R. Title: Neuroendokrine Tumors of the hindgut Source: Best Practice & Research Clinical Gastroenterology, Volume 19, Issue 5, Pages 739-751 2.3.3.6. Author(s): A. Ferlito, K. Devaney, A. Rinaldo Title: Neuroendocrine neoplasms of the larynx: Advances in identification, understanding, and management Source: Oral Oncology, Volume 42, Issue 8, Pages 770-788 2.3.3.7. Author(s): E. Kurt, C. Sezgin, T. Evrensel, U. Yalcinkaya, O. Kanat, A. Veral, M. Demiray, M. Arslan, B. Karabulut, I. Ercan, E. Goker, O. Manavoglu Title: Therapy, outcome and analysis of c-kit expression in patients with extrapulmonary small cell carcinoma Source: International Journal of Clinical Practice; 2005; 59 (5), 537 543. 2.3.3.8. Author(s): Chen JW, Yuan L, Hu HH Title: Small cell undifferentiated carcinoma in the epididymis Source: Chinese Medical Journal 2005; 118(16): 1402-1404 2.3.3.9. Author(s): Author(s): Vogelsang H., Siewert I.R. Title: Neuroendokrine Tumoren des Kolons und Rektums, Mit Ausnahme der Appendix Source: MULTİ MODALİTY TREATMENT RESULTS Onkologe 2004-10:1069-1078 2.3.3.10. Author(s): Kim KO; Lee HY; Riyu MH; Shin SJ; Kim MK; Lee KH; Hyun MS; Bae HS; Ryoo HM. Title: Extrapulmonary small-cell carcinoma Source: J Korean Med. Sci. 2006; 21: 833-7 2.3.3.11. Author(s): Lee SS; Lee JL; Riyu HM; Chang HM; Tae WK; Jung SL; Jang SJ; Khang SK; Kang YK Title: Extrapulmonary small cell carcinoma: Single center experience with 61 patients Source: Acta Oncologica, Volume 46, Issue 6 2007, pages 846 851 2.3.3.12. Author(s): M. Yashi, F. Terauchi, A. Nukui, M. Ochi, M. Yuzawa, Y. Hara, T. Morita Title: Small-cell neuroendocrine carcinoma as a variant form of prostate cancer

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