GÜLİN AMASYA KİŞİSEL BİLGİLER Pozisyonu Araştırma Görevlisi Doğum Yeri Nazilli AYDIN Telefon (İş) (312) 203 31 63 e-posta gamasya@pharmacy.ankara.edu.tr gulinamasyaphd@gmail.com Adres Ankara Üniversitesi, Eczacılık Fakültesi, Farmasötik Teknoloji Anabilim Dalı, Tandoğan, 06100, ANKARA EĞİTİM DURUMU Doktora Derecesi Ankara Üniversitesi Eczacılık Fakültesi, Farmasötik Teknoloji Anabilim Dalı 2009-2014 Yüksek Lisans Derecesi Ankara Üniversitesi Eczacılık Fakültesi, Farmasötik Teknoloji Anabilim Dalı 2005-2008 Lisans Ankara Üniversitesi Eczacılık Fakültesi 2001-2005 Orta Öğretim Aydın Lisesi (Yabancı Dil Ağırlıklı Bölüm) 1997-2001 MESLEKİ AŞAMA VE FAALİYETLER Araştırma Görevlisi Aralık 2005 -... Ankara Üniversitesi Eczacılık Fakültesi, Farmasötik Teknoloji Anabilim Dalı
Yüksek Lisans Tezi Ekim 2008 Tez Başlığı Ağız İçi Ülserlerinin Tedavisinde Kortikosteroit İçeren Mukoadezif İlaç Taşıyıcı Sistemlerin Geliştirilmesi Tez Danışmanı Tez Dönemi boyunca alınan destekler Prof. Dr. Nilüfer TARIMCI TÜBİTAK 2210 Yurt İçi Yüksek Lisans Burs Programı Doktora Tezi Eylül 2014 Tez Başlığı Deri Kanserlerinin Tedavisinde Uygulanmak Üzere 5- Florourasil İçeren Lipid Nanopartiküllerin Tasarımla Kalite Çalışmaları ve Değerlendirilmeleri Tez Danışmanı Prof. Dr. Nilüfer TARIMCI Misafir Araştırıcı Nisan 2013 Temmuz 2013 University of Pavia, Department of Drug Sciences, - Prof. Carla Caramella, Pavia, İtalya Eylül 2017 Aralık 2017 University Paris-Est Creteil - Institute of Chemistry and Materials Prof. Catherine Amiel, Paris, Fransa Projeler 1) TÜBİTAK 1001 Araştırma Projesi (Bursiyer) Nisan 2011 Ekim 2012
Kalsipotriol ve Klobetazol Propionatın Sabit Dozda Kombine Kullanımının in vitro Antipsöriatik Etkinliğinin İnsan Epidermal Keratinosit Hücrelerinde Değerlendirilmesi 2) Ankara Üniversitesi Teknoloji Geliştirme Bölgesi ANKÜR Projesi (Araştırıcı) Ekim 2014 Mart 2015 İki Farklı Tipteki Mamul Kozmetik Ürün Formülasyonunun Optimizasyonu 3) Ankara Üniversitesi BAP - Bilimsel Araştırma Projesi (Yardımcı Yönetici) Mayıs 2013 Şubat 2016 Deri kanserlerinin Tedavisinde Topikal Nanopartiküler Sistemlerin Geliştirilmesine Yönelik Çalışmalar 4) Ankara Üniversitesi BAP - Bilimsel Araştırma Projesi (Yönetici) Mayıs 2018 Devam Ediyor Yeni Nesil Hiyerarşik Lipid Nanopartikül Formülasyonlarının Geliştirilmesi Burslar&Ödüller Amgen Travelship AAPS 2014 Annual Meeting and Exposition, 2-6 Kasım 2014, San Diego, CA, ABD The International Pharmaceutical Federation (FIP) Travel Grand 75th FIP, World Congress of Pharmacy and Pharmaceutical Sciences, 29 Eylül 3 Ekim 2015, Düseldorf, ALMANYA Fransa Türkiye Büyükelçiliği - Sejour Scientifique de Haut Niveau (SSHN) doktora sonrası araştırma bursu Araştırma Alanları İlaç Taşıyıcı Sistemlerin Geliştirilmesi Nano İlaç Taşıyıcı Sistemler Perkütan Absorbsiyon Kozmetik Formülasyonların Geliştirilmesi Tasarımla Kalite Çalışmaları, QbD Hücre Kültürü
YAYIN VE BİLDİRİLER Uluslararası Dergilerde Yer Alan Yayınlar (SCI kapsamında) 1- Amasya G., Karavana S.Y., Sen T., Baloglu E., Tarimci N. (2009). A comparision of mechanical properties of buccal gel formulations based on different bioadhesive polymers, European Journal of Pharmaceutical Science, Supplement: S 38:(1) 105-106. 2- Badilli U., Amasya G., Ozkan S., Tarimci N. (2013). Simultaneous determination of Clobetasol Propionate and Calcipotriol in a novel fixed dose emulgel formulation by LC- UV. Chromatographia, 76:(3-4), 133-140. 3- Badilli U., Amasya G., Sen T., Tarimci N. (2014). Topical emulgel formulation containing inclusion complex of calcipotriol with cyclodextrin. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 78:(1-4), 249-255. 4- Badilli U., Onay-Besikci A., Amasya G., Sen T., Tarimci N. (2015). Calcipotriol captisol inclusion complex and corticosteroid in a novel fixed dose combination: evaluation on human epidermal keratinocyte cells. Journal of Inclusion Phenomena and Macrocyclic Chemistry; 83 (3): 363-368. 5- Amasya G., Sandri G., Onay-Besikci A., Badilli U., Caramella C., Bonferoni M.C., Tarimci N. (2016). Skin Localization of Lipid Nanoparticles (SLN/NLC): Focusing The Influence of Formulation Parameters. Current Drug Delivery, 13(7): 1100 1110. 6- Amasya G., Badilli U., Aksu B., Tarimci N. (2016). Quality by design case study 1: Design of 5-fluorouracil loaded lipid nanoparticles by the W/O/W double emulsionsolvent evaporation method. European Journal of Pharmaceutics. 84: 92-102. 7- Gumustas M., Turk C.T., Badilli U., Amasya G., Ozkan S., Tarimci N. (2017). Optimization Of Stability Indicating LC Method For The Sensitive In Vitro Determination From Solid Lipid Nanoparticles And Ex Vivo Analysis From Rat Skin Of Etofenamate. Current Pharmaceutical Analysis. 13 (1): 63-71. 8- Badilli U., Turk C.T., Amasya G., Tarimci N. (2017). Novel drug delivery system for dermal uptake of etofenamate: semisolid SLN dispersion. Current Drug Delivery. 14(3): 386-393. 9- Amasya G., Gumustas M., Badilli U., Ozkan S., Tarimci N. (2018). Development of a HILIC method for the determination of 5-fluorouracil from nano drug delivery systems and rat skin extracts. Journal of Pharmaceutical and Biomedical Analysis. 30(154): 285-293. Ulusallararası Hakemli Dergilerde Yer Alan Yayınlar 1- Amasya G., Karavana S.Y., Sen T., Baloglu E., Tarimci N. (2012). Bioadhesive and mechanical properties of triamcinolone acetonide buccal gels. Turkish Journal of Pharmaceutical Sciences. 9 (1), 1-12.
2- Sen T., Amasya G., Tarimci N. (2015). Triamcinolone Acetonide Buccal Bilayered Discs for Treatment of Erosive Oral Lichen Planus: Design and In Vitro Characterization. Turkish Journal of Pharmaceutical Sciences. 12(2):137-146. Kitap Bölümleri 1- Amasya G., Sen T., Tarimci N. (2009). Improvement of bioadhesiveness of chitosan by means of HPMC, Advances in Chitin Science, Eds: F. Rustichelli, C. Caramella, S. Şenel. K.M. Vårum, Vol:11, p: 133-138. Uluslararası Poster Sunumları 1- Amasya G., Kilic C. S., Tarimci N., Coskun M., Akalın K., Semizoglu S., An alternative dermal delivery system for cosmeceuticals. 6th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 7-10 April 2008, Barcelona, SPAIN. 2- Amasya G., Sen T., Tarimci N., Improvement of bioadhesiveness of chitosan by means of HPMC. 9th International Conference of the European Chitin Society, 23-26 May 2009, San Servolo Island, Venice, ITALY. 3- Amasya G., Sen T., Tarimci N., The effect of enhancers on the mucoadhesive drug delivery systems. Pharmscifair, 8-12th June 2009, Nice, FRANCE. 4- Bozkır A., Basaran B., Coban S., Hinc C., Amasya G., The Preparation and characterization of poly(lactide-co-glycolide)microsperes containing ovalbumin, 9th International Symposium on Pharmaceutical Sciences, 23-26 June 2009, Ankara, TURKEY. 5- Amasya G., Karavana S. Y., Sen T., Baloglu E., Tarimci N., A comparision of mechanical properties of buccal gel formulations based on different bioadhesive polymers, 3rd BBBB International Conference On Pharmaceutical Science, 26-28 October 2009, Antalya, TURKEY. 6- Amasya G., Sen T., Tarimci N., A new delivery system for the treatment of oral mucosal ulcers, 7th World Meeting on Pharmaceutics, Biopharmaceutics and pharmaceutical technology, 8-11 March 2010, Valetta, MALTA. 7- Amasya G., Sen T., Tarimci N., Desing and evaluation of chitosan buccal discs, 3rd PharmSciFair, 13-17 June 2011, Prague, CZECK REPUBLIC. 8- Badilli U., Amasya G., Ozkan S., Tarimci N., High performance liquid chromatographic determination of clobetasol propionate and calcipotriol in a fixed dose combination formulation, 16th International Pharmaceutical Technology Symposium (IPTS-2012), 10-12 September 2012, Antalya, TURKEY. 9- Badilli U., Amasya G., Sen T., Tarimci N., Solubility enhancement of calcipotriol with Captisol, The 9th Central European Symposium on Pharmaceutical Technology (CESPT 2012), 20-22 September 2012, Dubrovnik, CROATIA. 10- Amasya G., Badilli U., Tarimci N., Solid lipid nanoparticles of 5-fluorouracil for skin cancer, 3rd Conference on Innovation in Drug Delivery: Advances in Local Drug Delivery, 22-25 September 2013, Pisa, ITALY.
11- Badilli U., Besikci Onay A., Amasya G., Sen T., Tarimci N., In Vitro Antipsoriatic Activity Of Fixed-Dose Combination Of Calcipotriol And Clobetasol Propionate, AAPS Annual Meeting and Exposition, 2-6 November, 2014, San Diego, USA. 12- Amasya G., Sandri G., Besikci Onay A., Badilli U., Caramella C., Bonferoni C., Tarimci N., Qualitative And Quantitative Skin Effects Of Lipid Nanoparticles, AAPS Annual Meeting and Exposition, 2-6 November, 2014, San Diego, USA. 13- Sen T., Amasya G., Badilli U., Tarimci N., (2015). Preparation And Evaluation of NLC Contained Argan Oil and Inutec Sp1, Nanobiotechnology Days, 14-15 May 2015, Kemerburgaz University,Faculty of Pharmacy, İstanbul. 14- Kaymakci M.T., Amasya G., Tarimci N., Preformulation Studies of Oral Disintegrating Tablet (ODT) Containing Flurbiprofen-β Cyclodextrin Complex, 11 th International Symposium on Pharmaceutical Sciences (ISOPS-11), 9-12 June 2015, Ankara-TURKEY. 15- Sen T., Badilli U., Inal O., Amasya G., Ozturk C., Cakır K., Tarimci N., Availability of argan oil as liquid lipid in NLC formulations to improve skin hydration, 11 th International Symposium on Pharmaceutical Sciences (ISOPS-11), 9-12 June 2015, Ankara-TURKEY 16- Badilli U., Sengel-Turk C.T., Amasya G., Tarimci N., Occlusive and Mechanical Characteristics of Etofenamate Encapsulated Semisolid SLN Formulations, 11 th International Symposium on Pharmaceutical Sciences (ISOPS-11), 9-12 June 2015, Ankara-TURKEY 17- Amasya G., Gumustas M., Sengel-Turk C.T., Badilli U., Ozkan S.A., Tarımci N., Optimization of Sensitive and Selective RP-LC Method For The Determination Of Etofenamate From Rat Skin, 18th The European Conference on Analytical Chemistry, Euroanalysis 2015, 6 10 September 2015, Bordoeux, FRANCE. 18- Amasya G., Aksu B., Badilli U., Tarımci N., Optimization of 5-Fluorouracil Loaded Solid Lipid Nanoparticle (SLN) Formulations Based on Artificial Neural Network 6th BBBB Conference on Pharmaceutical Sciences Strategies To Improve The Quality And Performance Of Modern Drug Delivery Systems September 10-12, 2015, Helsinki, Finland (Oral Presentation). 19- Amasya G., Badilli U., Tarımci N., The Combination of the Best Fitted Emulsification Method For Producing SLN with the w/o/w Double Emulsion - Solvent Evaporation Method, 75th FIP World Congress of Pharmacy and Pharmaceutical Sciences 2015, 29 September - 3 October 2015, Düsseldorf, GERMANY. 20- Amasya G., Badilli U., Aksu B., Tarımci N., Evaluation of 5-Fluorouracil Loaded Lipid Nanoparticles for Skin Cancer: A Quality by Design Approach by Using Artificial Neural Network Program, AAPS Annual Meeting and Exposition, 25-29 November, 2015, Orlando, FLA, USA. 21- Badilli U., Sengel-Turk C. T., Amasya G., Tarimci N., Dermal Behaviour of Semisolid SLN Dispersions of Etofenamate, International Gazi Pharma Symposium, GPSS, 21-15 November 2015, Antalya, TURKEY. 22- Amasya G., Badilli U., Onay-Besikci A., Tarımci N., Lipid Nanoparticle Based Carbopol Gel for Topical Chemotherapy of 5-Fluorouracil, Skin Forum 2016 Annual Meeting, 21-22 June 2016, UCL School of Pharmacy, London, ENGLAND.
23- Amasya G., Badilli U., Aksu B., Tarımci N., Computational Approaches To Estimate NLC Formulation: Artificial Neural Network, 18th International Pharmaceutical Technology Symposium (IPTS-2016), 18 21 September, 2016, Antalya, TURKEY. 24- Amasya G., Aksu B., Badilli U., Tarımci N., An Implementation Of Artificial Neural Network: Physicochemical Characterization Of Lipid Nanoparticles, 4th Congress on Innovation in Drug Delivery, Site-Specific Drug Delivery,25-28 September, 2016, Antibes-Juan-les-Pins, FRANCE. 25- Amasya G., Badilli U., Aksu B., Tarımci N., QbD Guided Early Pharmaceutical Development Study: Production of Lipid Nanoparticles by High Pressure Homogenization, 2nd European Conference on Pharmaceutics, 3-4 April 2017, Krakow, POLAND. 26- Erkan Ö., Amasya G., Sezgin-Bayındır Z., Yüksel N., Formulation development and evaluation of S-Adenosyl-L-methionine loaded solid lipid nanoparticles using different lipid carriers, BIOMED2017 22nd International Biomedical Science&Technology Symposium, 12-14 May 2017, Ankara TURKEY. 27- Amasya G., Aksu B., Badilli U., Tarımci N, Artificial Intelligence Based Optimization Of Lipid Nanoparticles, 6th FIP Pharmaceutical Sciences World Congress, 21-24 May, 2017, Stockholm, SWEDEN. 28- Amasya G., Gümüştaş M., Badilli U., Tarımci N., Ozkan S.A., Optimization And Validation Of HPLC Method for the Determination of 5-fluorouracil from Lipid Nanopartıcles and Rat Skın Extratcs, XXVIII International Symposium on Pharmaceutical and Biomedical Analysis (PBA2017), 2-5 July 2017, Madrid, SPAIN. 29- Amasya G., Badilli U., Aksu B., Tarımci N., QbD Implementation for Obtaining 5 Fluorouracil Loaded NLC Formulation. 2017 Controlled Release Society Annual Meeting, 16-19 July 2017, Boston, USA. 30- Amasya G., Sengel-Turk C. T., Badilli U., Tarimci N., Design And optimization of Fluticasone Propionate Loaded Solid Lipid Nanoparticles By 3 2 Factorial Design. International Gazi Pharma Symposium, GPSS, 11-13 October 2017, Ankara, TURKEY. 31- Gumustas M., Amasya G., Badilli U., Ozkan S.A., Tarimci N., Validation of a HILIC Method for the Analysis of 5-Fluorouracil Loaded Lipid Nanoparticles and Application to In Vitro and Ex Vivo Tests, EastWest Chemistry Conference, October 12-14 2017, Skopje, MACEDONIA. 32- Gumustas M., Amasya G., Badilli U., Ozkan S.A., Tarimci N., Validation of HPLC Methods for the Analysis of Nanoparticle Based Drug Delivery Systems, 8th Annual Symposium on Physical and Analytical Chemistry, 28-29 December 2017, Tbilisi, GEORGIA. Uluslararası Sözlü Sunumlar 1- Amasya G., Quality by Design Studies and Evaluation of Lipid Nanoparticles Containing 5-Fluorouracil in the Treatment of skin Cancers 18th International Pharmaceutical Technology Symposium (IPTS-2016), 18 21 September, 2016, Antalya, TURKEY. KİŞİSEL YETENEK VE BECERİLER
Yabancı Diller İngilizce İyi Derecede ODTÜ Yabancı Diller Yüksek Okulu Genel Amaçlı İngilizce Kursu Upper Intermediate Level, 2009, Ankara. İtalyanca Başlangıç seviyesi Ankara Üniversitesi TÖMER Türkçe ve Yabancı Dil Uygulama ve Araştırma Merkezi, 2013, Ankara. Fransızca Başlangıç seviyesi Mesleki Üyelikler Farmasötik Teknoloji Araştırmacıları Derneği (TÜFTAD) Kontrollü Salım Sistemleri Derneği (KSSD) American Association of Pharmaceutical Scientists (AAPS)