CURRICULUM VITAE ISMAIL SAVAS MD.

CURRICULUM VITAE ISMAIL SAVAS MD. OCCUPATION ADDRESS: Ankara University School of Medicine Department of Chest Diseases and Tuberculosis Mamak caddesi 06100 Dikimevi Ankara Türkiye HOME ADDRESS: Ahmet Yesevi caddesi. Yamaçevler Sitesi 8/16 Dikmen- Çankaya Ankara Türkiye 06460 DATE OF BIRTH: 27.02.1963 PLACE OF BIRTH: Ankara,Turkey CITIZENSHIP: Turkish MARITAL STATUS: Married CURRENT POSITION: Professor in Pulmonary Medicine,Ankara University EDUCATION: Primary School: Ankara Kurtuluş Primary School High School: Ankara Kurtuluş High School Medical School: Ankara University, School of Medicine Postgraduating training: Pulmonology Department at Ankara University School of Medicine Department of Chest Diseases and Tuberculosis Internal Medicine rotations ( 12 months) Foreign Languages: English

Educational experiences: 1) I worked in Birmingham,England for 3 months about the results of the pulmonary infections on immune functions. 2) I spent a 6 months in Ulukışla,Niğde (rural area in Turkey) as a general practitioner. 3) I finished my postgraduate education in 1992 4) I completed my obligatory mission in Diyarbakır,Turkey in the Diyarbakır Chest Hospital for 1 year). 5) I became a associate professor in the department of chest diseases and tuberculosis in 1995. 6) I did a research about gene therapy in lung cancer for 1 year in New York University,USA. 7) I obtained the title of Professor in Pulmonary Medicine 2001. 8) I worked in New Zealand at Middlemore Hospital with Dr.Conroy Wong in 2011 for 3 months about the subject of Chronic Care. Membership in professional organizations: Turkish Tuberculosis and Thorax Society Turkish Thoracic Society Turkish Association of Respiratory Researchers Medical Doctors Chamber of Ankara International association for the Study of Lung Cancer National projects (Recents ) 1) Turkish Lung cancer epidemiology studies ( 2004-2006 ) sponsored by Turkish Thoracic Society 2) Gene polymorphism in patients with venous thrombolism. (2009----) sponsored by TUBITAK 3) Endobronchial ultrasonography in patient with mediastinal lymphadenopathy ( 2010-2012 ) sponsored by Ankara University. I am interested in Bronchoscopy, chronic obstructive pulmonary diseases, lung cancer, smoking and smoking cessation, pulmonary function tests, pulmonary artery diseases. 2

PUBLICATIONS A)NATIONAL 1.Numanoglu N., Kara E., Alper D., Yucel E., Karabıyıkoglu G., Ozenci M., Savas I., Ercan A: The lungs in mitral stenosis. Sosyal Sigortalar Kurumu Tıp Bülteni. 1988; 6(3):27-33. 2.Savas I., Özdemir Ö., Numanoğlu N., Alper D: A case: Mucoid impaction. Tüberküloz ve Toraks.1989; 37(1):85-88. 3.Savas I., Numanoğlu N., Özdemir Ö., Alper D., Mertol H., Erden A., Gönüllü U : Computerized tomography in the diagnosis of bronchiectasis. Tüberküloz ve Toraks. 1989;37(2):96-102. 4.Savas I., Pınar E., Numanoğlu N., Alper D., Özdemir Ö., Mertol H., Erden A., Altınörs M: The value of Computerized tomography in Silicosis. Tüberküloz ve Toraks.1989; 37(2):112-118 5. Savas I.,Alper D., Numanoğlu N., Özdemir Ö., Gönüllü U., Altuntaş Ö : The enlargement of parotid gland during treatment of brochospasm. Tüberküloz ve Toraks 1989;37(3):195-202. 6. Savas I., Saygun N., Alper D., Erdem B., Numanoğlu N., Özdemir Ö: The role of Neisseria catarrhalis in the lower respiratory infections. Tüberküloz ve Toraks.1989; 37(3): 203-207. 7.Gonüllü U., Savas I., Özdemir Ö., Numanoğlu N., Beder S., Alper D: Transtrakeal and transcarineal needle aspiration in the diagnosis of pulmonary malignancy. Tüberküloz ve Toraks.1990;38(2):79-86 8.Gönüllü U., Savas I., Özdemir Ö., Akyar S., Numanoğlu N., Erden İ., Alper D: Computerized tomography in the evaluation of pulmonary sarcoidosis.tüberküloz ve Toraks. 1990;38(2):105-110. 9.Gönüllü U., Özdemir Ö., Alper D., Beder S., Numanoğlu N., İçli F., Savas I: The bronchoscopic findings in metastatic lung cancer.tüberküloz ve Toraks.1990; 38(2):111-115. 10.Gönüllü U., Savas I., Özdemir Ö., Numanoğlu N., Yavuzer Ş.,Alper D: A case of epifirenic diverticule.tüberküloz ve Toraks. 1990; 38(2):125-128. 11.Gönüllü U., Savas I., Özdemir Ö., Numanoğlu N., Karabıyıkoğlu G., Alper D: The effects of styrene on pulmonary system. Tüberküloz ve Toraks.1990; 38(3):157-167. 12.Altuntaş Ö., Gönüllü U., Savas I., Özdemir Ö., Numanoğlu N., Alper D: The comparison of computerized tomography, broncoscopy and operation findings in patients with lung cancer and other pulmonary diseases.tüberküloz ve Toraks.1990; 38(3):189-196. 3

13.Gönüllü U., Savas I., Özdemir Ö., Numanoğlu N., Alper D: Two cases of Pulmonary Aplazi.Tüberküloz ve Toraks.1990; 38(4) :293-300. 14.Gönüllü U., Savas I., Özdemir Ö., Numanoğlu N., Alper D: Pulmonary Aspergilloma: 4 Cases.Tüberküloz ve Toraks.1990; 38(4):301-307. 15.Gönüllü U., Numanoğlu N., Özdemir Ö., Savas I.,Erkam Ü: Sulbactam/Ampicillin combination in the treatment of lower repiratory infections. Türkiye Klinikleri Tıp Bilimleri Araştırma Dergisi. 1991;9(1):1-4. 16. Savas I., Saygun N., Özsan M., Özdemir Ö., Gönüllü U., Numanoğlu N.,Alper D: Neisseria infections in the respiratory systems. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1991;44(4) :585-592. 17. Savas I., Özdemir Ö., Gönüllü U., Numanoğlu N., Beder S., Alper D., Gürses H : 819 patients.lung cancer series between 1981-1989. Tüberküloz ve Toraks.1991;39(2) :77-85. 18.Gönüllü U.,Özdemir Ö., Alper D., Numanoğlu N., Akay H., Uysal A., Savas I: A case of pulmonary hemosiderosis. Tüberküloz ve Toraks.1991; 39(2):109-115. 19.Gönüllü U., Alpman A., Savas I., Özdemir Ö., Numanoğlu N., Alper D: Swyer- James (Macleod) Syndrome. Tüberküloz ve Toraks.1991; 39(3) :205-214. 20.Özşahin S., Keleşoğlu A., Savas I., Karabıyıkoğlu G : Errors in using of metered dose inhaler. Tüberküloz ve Toraks.1992;40(3) :173-184. 21. Savas I., İmirzalıoğlu N., Şaylı BS., Numanoğlu N., Özdemir Ö., Alper D., Gürses H : Cytogenetic studies in malign pleural effusions. Tüberküloz ve Toraks.1992;40(3):185-197. 22. Savas I., Çobanlı B., Alper D., Taşkın A., Akal M: The series of patient undergoing surgery between 1989-1991 in our clinics. Tüberküloz ve Toraks.1992; 40(4):240-248. 23. Savas I., Özdoğan S: Epidemiologic data of our patients in 1991. Tüberküloz ve Toraks.1992; 40(4):250-262. 24.Özdoğan S., Savas I: Smoking habits in our patients. Tüberküloz ve Toraks.1993; 41(1): 35-44. 25.Numanoğlu N., Gönüllü U., Özdemir Ö., Savas I., Çelenk M., Atakurt Y., Alper D., Gürses H: The differentiation of pleural fluid. Tüberküloz ve Toraks.1993;41(2):113-120. 26.Numanoğlu N., Gönüllü U., Özdemir Ö., Savas I.,Şimşek C., Atakurt Y., Alper D., Pınar E., Enacar N : Pulmonary Findings and Pneumoconiosis in 12 300 Coal Miners.. DOĞA Turkish Journal of Medical Sciences. 1993;19(3):227-238. 4

27. Savas I., Özdoğan S., Erduran Ş., Gürses H : Resistant tuberculosis cases in Ankara between 1988-1993. XX. Tüberküloz ve Göğüs Hastalıkları Kongre Kitabı.1994; 600-618. 28.Çıray N., Savas I., Güliter S., Özdemir Ö., Gönüllü U., Numanoğlu N., Şaylı BS., Tekelioğlu M., Alper D : Ultrastructural changes in Immotile Cilia Syndrome. Ankara Üniversitesi Tıp Fakültesi Mecmuası.1994; 47(1) :143-154. 29. Savas I., Saygun N : Bacteriologic evaluation of the patient with tuberculosis between 1984-1993 in Ankara University, The Dept of Chest Diseases. Tüberküloz ve Toraks.1994; 42(4) :244-247. 30. Savas I., Çelik G., Güngör A., Gönüllü U., Özdemir Ö., Numanoğlu N., Alper D., Gürses H : Cyst hydatic diseases between 1986-1993. Tüberküloz ve Toraks.1994; 42(4) :231-235. 31.Saygun N., Zamani A., Savas I., Saygun M : Invitro susceptibility Mycobacterium Tuberculosis to Ampicillin/ Sulbactam. The Journal of Ankara Medical School.1995;17(4):283-286. 32. Savas I: Oncogenes. Türkiye Klinikleri Tıp Bilimleri Dergisi. 1995;15(6):374-377. 33.Çelik G., Savas I., Kaya A., Özşahin S., Numanoğlu N., Gönüllü U., Sabır H: The effect of diesel exhaust on the lung. Tüberküloz ve Toraks.1998; 46(2):105-114. 34.Turkish Thoracic Society, Working group. The consensus report of Community acquired pneumonia. Klimik Derg.1998;11:4-10. 35.Arbak P.,Karacan Ö.,İdilman R.,Kaya A., Savas I.,Numanoğlu N: Pulmonary fibrosis (12 cases ).Tüberküloz ve Toraks 2000;48(1):57-62. 36. Savas I.,Kaya A.,Gürkan UÖ.,Eriş B.,Gönüllü U: s-icam-1 in nonsmall cell lung cancer.tüberküloz ve Toraks. 2000;48(4):306-311. 37.Öner F., Savas I.,Numanoğlu N: Adenocancer case.tüberküloz ve Toraks.2000; 48(4):349-352. 38.Ülger F., Savas I: Pulmonary Thromboemboli. Türkiye Klinikleri Cerrahi Dergisi.2000; 5(2):85-92. 39. Çelebioğlu B., Gürkan ÖU., Gönüllü U., Savas I., Atakul T., Kurtman C: Brachytherapy application in lung cancer. Solunum Hastalıkları. 2000; 11(4):354-358 40. Savas I:Community acquired pneumonia. Actuel Medicine.2002;10(2):33-42. 41. Savas I: The treatment of lung cancer. Actuel Medicine.2002;10(12):56-65. 42. Savas I: Systemic lupus eritemathosus and lungs. Turkish Clinics J Int Med Sci. Immunology and Rheumotalogy.2005;1(8):26-29. 5

43. Savas I: Acute pulmonary thromboemboli. (Emergency Medicine Special issue) Turkish Clinics J Surg Med Sci 2006, 2(11):50-57. 44. Savas I, Kaya A : Symptoms and signs in lung cancer. Turkish Clinics J Surg Med Sci 2006, 2(12):66-71. 45. Savas I.,Can B: Etiology, clinical findings and symptoms in malign pleural mesothelioma. Turkish Clinics, Chest Surgery special edition. 2008;1(1):9-17. 46.Köycü G., Savas I:Malign Plevral Mezotelyomada prognostik etkenler. Turkish Clinics, Chest Surgery special edition. 2008;1(1):58-64. B)INTERNATIONAL 1.Özdemir Ö., Gönüllü U.,Numanoğlu N., Savas I., Alper D.,Gürses H: Chronic Effects of Welding Exposures on Respiratory Symptoms and Pulmonary Function Tests. Journal of Occupational and Enviromental Medicine. 1995;52(12):800-803. 2.Gönüllü U.,Güngör A., Savas I., Özdemir Ö., Moğulkoç G.,Alper D.,Yavuzer Ş: Huge Thymic Cysts. The J Thorac and Cardivasc Surgery. 1996; 112(3):835-836. 3. Savas I.,Şen E.,Gönüllü U.,Çelebioğlu B: Postbrachytherapy regression. J of Bronchology.2000;7(1):85-86. 4.Atalay F.,Baltacı V.,Alpas I., Savas I.,Atikcan S.,Balcı S: Sister chromatid exchange rate from pleural fluid cells in patients with malignant mesothelioma. Mutation Research. 2000; 465:159-163. 5.Çakır M.,Gürkan OU., Savas I.,Numanoğlu N.,Ataman S.,Ekinci C.,Akar N:Extensive jugular and upper limb thrombosis in a patient with factor V Leiden mutation and non-hodgkin s lymphoma. Aust N Z J Med 30(6):735-736,2000. 6. Savas I.,Ural ÖG.,Savaş H.,Eriş B.,Gönüllü U.,Numanoğlu N: Urine deoxypyridinoline level:an alternative to Bone Scan in lung cancer. Clin Biochem. 2000;33(7):591-593. 7.Aras S.,Baltacı V.,Yıldırım Ö., Savas I.,Alpas I.,Şen E: Glutathione S-Transferase M1 and T1 gene polymorphism in patients with lung cancer among Turkish population. Biotechnology and technology Equipment. 15(2):54-61,2001. 8.İdilman R., Çetinkaya H., Savas I., Aslan N.,Dizbay S.,Baştemir M., Sarıoğlu M.,Soykan I.,Bozdayı M., Colantoni A., Aydıntuğ O., Bahar K., Uzunalimoğlu Ö.,Thiel DH., Numanoğlu N., Dökmeci A: Bronchoalveolar lavage fluid in individual with chronic hepatitis. J Med Virol,66:34-39, 2002. 9. Kaya A., Savas I., Şen E.,Dizbay Sak S.,Güngör A., Gönüllü U: Histiocytose X et adénocarcinome broncho-pulmonaire: rare coexistance. Can Respir J. 9(6): 431-6

432,2002. 10.Celebioğlu B.,Gürkan ÖU., Erdoğan S., Savas I.,Köse K.,Kurtman C.,Gönüllü U: High dose rate endobronchial brachytherapy palliates symptoms due to inoperable Lung cancer. Jpn J Clin Oncol 32(11):443-448,2002. 11. Savas I.,Baltacı V.,Şen E.,Aras S., Gürkan ÖU.,Alpas İ.,Yılmaz Z:The frequency of Factor V Leiden mutation in patients with lung cancer. Turkish Respiratory Journal,4(3):113-115,2003. 12.Kaya A.,Çiledağ A.,Gulbay BE.,Poyraz B.,Çelik G.,Şen E., Savaş H., Savas I: The prognostic significance of vascular endothelial growth factor levels in sera of nonsmall cell lung cancer patients. Respiratory Medicine 2004:98;632-636. 13.Yılmaz A, Savas I, Dizbay Sak S, Güngör A, Kaya A, Serinsöz E, Savaş B: Distribution of Bcl-2 gene expression and its prognostic value in non-small cell lung cancer. Tuberk Toraks. 2005;53(4):323-9. 14. Kaya A, Poyraz B, Celik G, Ciledag A, Gulbay BE, Savas H, Savas I: Vascular endothelial growth factor in benign and malignant pleural effusions.arch Bronconeumol. 2005 Jul;41(7):376-9. 15. Sen E.,Kaya A.,Erol S, Savas I.,Gonullu U: Lung cancer in women: Clinical features and factors related to survival. Tuberk Toraks. 2008;56(3):266-74 16. Sozener ZC.,Kaya A.,Atasoy C.,Kılıckap M.,Numanoglu N.,Savas I:Septic pulmonary embolism: three case reports. Monaldi Arch Chest Dis. 2008 Jun;69(2):75-7. 17.Çiledağ A.,Kaya A.,Yetkin Ö.,Poyraz B., Savas I.,Numanoğlu N., Savaş H: The prognostic value of serum epidermal growth factor receptor level in patients with nonsmall cell lung cancer. Tuberk Toraks. 2008,56 ( 4 ): 390-395. 18. Ergün D., Savas I., Ergün R., Kaya A.,Gülhan M: Lung cancer and family history. Tuberk Toraks. 2009; 57(3): 251-258. 19. Buller HR et al. and Cassiopea Investigators (Savas I) :Enoxaparine followed by once-weekly idrabiotaparinux vs. enoxaparine plus warfarin for patients with acute symptomatic pulmonary embolism: a randomized, double blind, double dummy, non inferiority trial. www.thelancet.com published online 2011; November 28 : 6736 (11):1-7. 20.Demir N.,Ciledag A.,Savas I: Akciğer Kanseri Tanı ve Evrelemesindeki Gelişmeler/ The improvement in lung cancer diagnosis and staging. Turkiye Klinikleri Arch Lung 2012;13(Suppl):S39-S47 21. Büller HR, Gallus AS, Pillion G, Prins MH, Raskob GE; Cassiopea Investigators (Savas I).: Enoxaparin followed by once-weekly idrabiotaparinux versus enoxaparin 7

plus warfarin for patients with acute symptomatic pulmonary embolism: a randomised, double-blind, double-dummy, non-inferiority trial. Lancet. 2012 Jan 14;379(9811):123-9. 22. Hokusai-VTE Investigators (Savas I), Büller HR, Décousus H, Grosso MA, Mercuri M, Middeldorp S, Prins MH, Raskob GE, Schellong SM, Schwocho L, Segers A, Shi M, Verhamme P, Wells P: Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism. N Engl J Med. 2013 Oct 10;369(15):1406-15. 23. Ozsu S, Ozlu T, Sentürk A, Uçar EY, Kırkıl G, Kadıoğlu EE, Altınsoy B, Saylan B, Selimoğlu HS, Dabak G, Tutar N, Uysal A; TUPEG Study Investigators ( Savas I). Combination and comparison of two models in prognosis of pulmonary embolism: Results from Turkey Pulmonary Embolism Group (TUPEG) study. Thromb Res. 2014 Mar 19. S0049-3848. 24. Demir N, Enon S, Turksoy VA, Kayaalti Z, Kaya S, Cangir AK, Soylemezoglu T, Savas I.Association of cadmium but not arsenic levels in lung cancer tumor tissue with smoking, histopathological type and stage. Asian Pac J Cancer Prev. 2014;15(7):2965-70. 8